Abstract:

D11S1760, D11S4102, D11S4116, D11S4207, D11S4162, D11S914, D11S4127, D11S917, D11S4146 and D11S915 of 10 short tandem repeat (STR) loci on chromosome 11 were analyzed by fluorescence-based gene scan technique to understand the genetic polymorphisms of those STR loci on chromosome 11 in a Han population in Shaanxi pro- vince. The results showed that the number of alleles and genotypes observed at loci D11S1760, D11S4102, D11S4116, D11S4207, D11S4162, D11S914, D11S4127, D11S917, D11S4146 and D11S915 were 17, 11, 15, 11, 4, 6, 7, 12, 11 and 13 for alleles and 41, 18, 36, 30, 8, 10, 16, 30, 29 and 32 for genotypes, respectively. All the 10 loci were in Hardy-Weinberg equilibrium. The heterozygosities of each STR locus was 86.72%, 67.95%, 83.90%, 85.96%, 58.18%, 57.63%, 72.60%, 72.73%, 77.87% and 86.40%. It concluded the 10 loci on chromosome 11 were relatively highly genetic polymorphic in Han populations and could provide useful markers for genetic studies.