[an error occurred while processing this directive]

HEREDITAS ›› 2010, Vol. 32 ›› Issue (1): 41-48.doi: 10.3724/SP.J.1005.2010.00041

• en • Previous Articles     Next Articles

The function of histone chaperones during development

ZHAO Zhan-Ke, WANG Yu-Feng   

  1. Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life Science, Huazhong Normal University, Wuhan 430079,China
  • Received:2009-04-28 Revised:2009-08-01 Online:2010-01-20 Published:2010-01-15
  • Contact: WANG Yu-Feng E-mail:yfengw@mail.ccnu.edu.cn

Abstract:

Histone chaperones may participate the decondensation and assembly of chromatins, thus regulate gene expression. They play important roles in almost all developmental processes, such as gametogenesis, fertilization, embryogenesis, growth and senescence. In this review, we used well studied examples to illustrate various functions of histone chaperones during developmental processes. Focus is given to nucleoplasmin, CAF-1, HIRA, ASF1/CIA, and NAP1.

Key words: Asf1/CIA, Histonechaperones, Nucleoplasmin, CAF-1, Hir/Hira