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HEREDITAS ›› 2010, Vol. 32 ›› Issue (5): 517-523.doi: 10.3724/SP.J.1005.2010.00517

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Development of 3-enzyme pyrosequencing system and its application in rapid diagnosis of Down’s syndrome

LIU Xi-Qun1, ZHU Shu-Hui2, ZOU Bing-Jie2, MA-Yin-Jiao2, ZHOU Guo-Hua1,2   

  1. 1. School of Basic Medical Sciences, Nanjing Medical University, Nanjing 210029, China; 2. Huadong Institute for Medicine and Biotechnics, Nanjing 210002, China
  • Received:2009-10-27 Revised:2010-01-09 Online:2010-05-20 Published:2010-05-05
  • Contact: ZHOU Guo-Hua E-mail:ghzhou@public1.ptt.js.cn

Key words: apyrase, 3-enzyme pyrosequencing method, Down’s syndrome, SNP (single nucleotide polymorphism)