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HEREDITAS ›› 2013, Vol. 35 ›› Issue (12): 1352-1359.doi: 10.3724/SP.J.1005.2013.01352

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sn-glycerol-3-phosphate acyltransferases (GPATs) in plants

LIU Cong1, XIAO Dan-Wang1, SHI Chun-Lin1, HU Xue-Fang1, WU Ke-Bin1, GUAN Chun-Yun1,2, XIONG Xing-Hua1,2   

  1. 1. Crop Gene Engineering Key Laboratory of Hunan Province, Hunan Agricultural University, Changsha 410128, China; 
    2. Hunan Branch of National Oilseed Crops Improvement Centre, Hunan Agricultural University, Changsha 410128, China
  • Received:2013-06-03 Revised:2013-09-09 Online:2013-12-20 Published:2013-11-25
  • Contact: XIONG Xing-Hua E-mail:xiongene@yahoo.com

Abstract:

sn-glycerol-3-phosphate acyltransferase (GPAT) catalyzes the acylation at sn-1 position of glycerol-3- phosphate to produce lysophosphatidic acid (LPA) in an acyl-CoA or acyl-ACP-dependent manner, which is the initial and rate-determining step of TAG biosynthetic pathway. Some GPATs have sn-2 transfer activity. Part members of the GPAT gene family have been cloned from different plant species. Based on their subcellular localizations, GPATs can be classified into three types, plastid GPATs, mitochondria GPATs and endoplasmic reticulum GPATs. GPATs exhibit diverse biochemical properties and are involved in synthesis of several lipids such as TAG, suberin, and cutin which play important roles in the growth and development of plants. This review summarized the current understanding of the chromosomal locus and gene structure of GPAT genes and the subcellular localization, sn-2 regiospecificity, substrates specialty, and functions of GPATs in plants.

Key words: GPAT genes, substrates specificity, sn-2 regiospecificity, GPATs function