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Hereditas(Beijing) ›› 2020, Vol. 42 ›› Issue (2): 212-221.doi: 10.16288/j.yczz.20-030

• Resource and Platform • Previous Articles     Next Articles

The 2019 novel coronavirus resource

Wenming Zhao1,2,3(), Shuhui Song1,2(), Meili Chen1,2(), Dong Zou1,2(), Lina Ma1,2(), Yingke Ma1,2, Rujiao Li1,2, Lili Hao1,2, Cuiping Li1,2, Dongmei Tian1,2, Bixia Tang1,2, Yanqing Wang1,2, Junwei Zhu1,2, Huanxin Chen1,2, Zhang Zhang1,2,3, Yongbiao Xue1,3(), Yiming Bao1,2,3()   

  1. 1. China National Center for Bioinformation & National Genomics Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China;
    2. CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
    3. University of Chinese Academy of Sciences, Beijing 100049, China
  • Received:2020-01-31 Revised:2020-02-07 Online:2020-02-20 Published:2020-02-08
  • Supported by:
    the National Key Research & Development Program of China(2016YFE0206600);the National Key Research & Development Program of China(2017YFC1201202);13th Five-year Informatization Plan of CAS(XXH13505-05);Strategic Priority Research Program of the Chines Academy of Sciences (CAS)(XDA19050302);Capacity building project of genome science data center of Chinese Academy of Sciences(0202);Key Technology Talent Program of the CAS, The Youth Innovation Promotion Association of Chinese Academy of Sciences

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Abstract:

An ongoing outbreak of a novel coronavirus infection in Wuhan, China since December 2019 has led to 31,516 infected persons and 638 deaths across 25 countries (till 16:00 on February 7, 2020). The virus causing this pneumonia was then named as the 2019 novel coronavirus (2019-nCoV) by the World Health Organization. To promote the data sharing and make all relevant information of 2019-nCoV publicly available, we construct the 2019 Novel Coronavirus Resource (2019nCoVR, https://bigd.big.ac.cn/ncov). 2019nCoVR features comprehensive integration of genomic and proteomic sequences as well as their metadata information from the Global Initiative on Sharing All Influenza Data, National Center for Biotechnology Information, China National GeneBank, National Microbiology Data Center and China National Center for Bioinformation (CNCB)/National Genomics Data Center (NGDC). It also incorporates a wide range of relevant information including scientific literatures, news, and popular articles for science dissemination, and provides visualization functionalities for genome variation analysis results based on all collected 2019-nCoV strains. Moreover, by linking seamlessly with related databases in CNCB/NGDC, 2019nCoVR offers virus data submission and sharing services for raw sequence reads and assembled sequences. In this report, we provide comprehensive descriptions on data deposition, management, release and utility in 2019nCoVR, laying important foundations in aid of studies on virus classification and origin, genome variation and evolution, fast detection, drug development and pneumonia precision prevention and therapy.

Key words: 2019nCoVR, 2019 novel coronavirus, China National Center for Bioinformation (CNCB), National Genomics Data Center (NGDC), genomic data sharing

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