利用CRISPR/Cas9系统构建FGF21基因敲除小鼠模型
刘旭(
),张平,张晓枫,李兴,白宇,贾克荣,郭晓东,张豪,马晓燕,仓明,刘东军,郭旭东
),张平,张晓枫,李兴,白宇,贾克荣,郭晓东,张豪,马晓燕,仓明,刘东军,郭旭东
Construction of FGF21 knockout mouse models by the CRISPR/Cas9 system
Liu Xu(),Zhang Ping,Zhang Xiaofeng,Li Xing,Bai Yu,Jia Kerong,Guo Xiaodong,Zhang Hao,Ma Xiaoyan,Cang Ming,Liu Dongjun,Guo Xudong
),Zhang Ping,Zhang Xiaofeng,Li Xing,Bai Yu,Jia Kerong,Guo Xiaodong,Zhang Hao,Ma Xiaoyan,Cang Ming,Liu Dongjun,Guo Xudong
图6. WT和Fgf21-/-小鼠毛发再生速度的比较和组织切片观察 A：WT小鼠毛发再生情况及组织切片观察;B~D：Fgf21-/-小鼠毛发再生情况及组织切片观察。红色框区为一个毛囊;WT：野生型小鼠;KO：Fgf21-/-小鼠。
Fig. 6. The comparison of the hair re-growth speed and paraffin sectionin WT and Fgf21-/- mice
