RAD51调控REV1参与DNA双链断裂修复

黄敏,杨业然,孙晓艳,张婷,郭彩霞

RAD51 regulates REV1 recruitment to DNA double-strand break sites

Huang Min,Yang Yeran,Sun Xiaoyan,Zhang Ting,Guo Caixia

图1 RAD51调控GFP-REV1到UVA诱导的DSBs位点的招募 A：U2OS细胞瞬时转染GFP-REV1。荧光检测结果显示GFP-REV1被招募至UVA诱导的DSBs损伤位点处。B：检测敲低RAD51对GFP-REV1招募的影响。数据为3次独立的生物学重复的统计结果。C：敲低RAD51的Western blot检测结果。Tubulin为内参对照。

Fig. 1 RAD51 regulates the recruitment of GFP-REV1 to laser-induced DSBs