白血病的精准基因组医学研究与转化应用

于雪新,陈艾莉,李玥莹,刘丹,王前飞

Precision genomic and translational medicine for acute myeloid leukemia

Yu Xuexin,Chen Aili,Li Yueying,Liu Dan,Wang Qianfei

图2 表观调控因子ASXL2通过组蛋白修饰在造血干细胞功能维持中起抑癌作用

Fig. 2 The epigenetic regulator ASXL2 plays a critical role in maintenance of normal HSC functions and suppression of myeloid malignancies via histone modification