唐氏综合征小鼠模型的遗传背景和应用
The genetic background and application of Down syndrome mouse models
唐氏综合征小鼠模型的遗传背景和应用 |
| 孟晓伟,汪洁,马晴雯 |
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The genetic background and application of Down syndrome mouse models |
| Meng Xiaowei,Wang Jie,Ma Qingwen |
| 图2 Ts65Dn小鼠易位染色体Mmu1716和Ts1Rhr小鼠重复片段简图 Ts65Dn-Mmu1716为Ts65Dn小鼠中重复片段,包含Mmu16上Mrpl39基因前端断裂点到端粒约13.4 Mb和Mmu17上Pde10a基因后端断裂点到着丝粒约9.4 Mb片段。Ts1Rhr-DSCR为Ts1Rhr小鼠中重复片段,包含Mmu16上Cbr1和Mx2基因间约3.9 Mb片段,与人类染色体中DSCR同源。 |
| Fig. 2 The trisomic segments represented in Ts65Dn and Ts1Rhr mouse models |
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