N-WASP通过polyPro和VCA结构域调控大脑皮层神经元迁移

沈秀莲,逯宜超,甲芝莲,吴强

N-WASP regulates cortical neuron migration through its polyPro and VCA domains

Shen Xiulian,Lu Yichao,Jia Zhilian,Wu Qiang

图1 N-WASP在小鼠皮层中的表达A：蛋白免疫印迹检测在胚胎发育过程中N-WASP蛋白的表达量,下方是对蛋白免疫印迹进行的定量分析;B：Cufflinks 2.1.1分析N-WASP在胚胎发育过程中mRNA水平。FPKM,fragments per kilobase of transcript per million mapped reads,每一百万个mapped reads中map到1kb转录本上的fragments个数。FPKM=cDNA fragments/(mapped reads(millions)× transcript length(kb))。

Fig. 1 The expression profile of N-WASP in mouse cortex