靶向miRNA前体不同类型sgRNA的丰度及特异性评估
刘海龙,谌阳,高杨,周玲,韩晓松,赵长志,杨高娟,陈毅龙,杨慧,谢胜松

Assessing abundance and specificity of different types of sgRNA targeting miRNA precursors
Liu Hailong,Shen Yang,Gao Yang,Zhou Ling,Han Xiaosong,Zhao Changzhi,Yang Gaojuan,Chen Yilong,Yang Hui,Xie Shengsong
表6 不同脱靶效应评估条件下猪miRNA前体及sgRNA靶点丰度特征
Table 6 The abundance of porcine miRNA precursor and corresponding sgRNA targets under different off-target evaluation criteria
筛选类型 含sgRNA靶点的miRNA前体数量(个) sgRNA的数量(个)
脱靶不严谨型 225 (28%) 1314 (24.5%)
脱靶严谨型 147 (18.2%) 676 (12.6%)