靶向miRNA前体不同类型sgRNA的丰度及特异性评估

刘海龙,谌阳,高杨,周玲,韩晓松,赵长志,杨高娟,陈毅龙,杨慧,谢胜松

Assessing abundance and specificity of different types of sgRNA targeting miRNA precursors

Liu Hailong,Shen Yang,Gao Yang,Zhou Ling,Han Xiaosong,Zhao Changzhi,Yang Gaojuan,Chen Yilong,Yang Hui,Xie Shengsong

图1 靶向miRNA前体不同类型sgRNA特征示意图 N代表A或T或C或G,R代表A或G,Y代表T或C,W代表A或T。红线条表示成熟miRNA。

Fig. 1 Illustrations of the different types of sgRNAs that target miRNA precursors