基于迁移学习的MHC-I型抗原表位呈递预测

胡伟澎,李佑平,张秀清

MHC-I epitope presentation prediction based on transfer learning

Hu Weipeng,Li Youping,Zhang Xiuqing

表2 Pluto与主流工具对免疫原性多肽的排名

Table 2 Immunogenic peptides ranked by Pluto and other popular methods

病人编号 多肽 HLA Pluto MixMHCpred NetMHCpan4.0 EL NetMHCpan4.0 BA MHCflurry 3903 AYHSIEWAI HLA-A2402 76 32 22 147 113 3998 KVDPIGHVY HLA-A0101 3 2 1 1 4 3998 KVDPIGHVYIF HLA-A0101 5 148 27 31 113 patient1 ALDPHSGHFV HLA-A0201 9 17 14 25 17 patient1 ALLETPSLL HLA-A0201 18 5 6 10 22 patient1 ALLETPSLLL HLA-A0201 3 20 12 16 29 patient2 ELMRDINSM HLA-B3501 128 107 57 30 45