组蛋白H3K27me3对骨骼肌发育调控研究进展

甘炎民,周健,全绒,洪林君,李紫聪,郑恩琴,刘德武,吴珍芳,蔡更元,顾婷

Histone H3K27me3 in the regulation of skeletal muscle development

Gan Yanmin,Zhou Jian,Quan Rong,Hong Linjun,Li Zicong,Zheng Enqin,Liu Dewu,Wu Zhenfang,Cai Gengyuan,Gu Ting

图1 H3K27me3抑制基因表达的作用机制 A：H3K27me3募集PRC1复合物抑制转录;B：H3K27me3促进DNA序列甲基化;C：H3K27me3对等位基因进行印记。

Fig. 1 The mechanism of H3K27me3 inhibiting gene expression