三代测序与靶向捕获技术联用进行高分辨HLA基因分型及MHC区域单倍体型精细鉴定
陈佳,舒明月,里进,付爱思,杨帆,王邹,李一荣,邓子新,刘天罡

The third-generation sequencing combined with targeted capture technology for high-resolution HLA typing and MHC region haplotype identification
Chen Jia,Shu Mingyue,Li Jin,Fu Aisi,Yang Fan,Wang Zou,Li Yirong,Deng Zixin,Liu Tiangang
表4 二代(Illumina)和三代(PacBio)测序数据中所有HLA基因phasing regions个数的差异
Table 4 Differences in the number of phasing regions of all HLA genes between the Next-(Illumina) and Third-(PacBio)generation sequencing technology
测序平台 单倍体分型区域数目
1 2 >3
Illumina 87 12 16
PacBio 103 4 4