三代测序与靶向捕获技术联用进行高分辨HLA基因分型及MHC区域单倍体型精细鉴定
The third-generation sequencing combined with targeted capture technology for high-resolution HLA typing and MHC region haplotype identification
三代测序与靶向捕获技术联用进行高分辨HLA基因分型及MHC区域单倍体型精细鉴定 |
| 陈佳,舒明月,里进,付爱思,杨帆,王邹,李一荣,邓子新,刘天罡 |
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The third-generation sequencing combined with targeted capture technology for high-resolution HLA typing and MHC region haplotype identification |
| Chen Jia,Shu Mingyue,Li Jin,Fu Aisi,Yang Fan,Wang Zou,Li Yirong,Deng Zixin,Liu Tiangang |
| 图6 HCC27 MHC区域的单倍体分型结果预测 consensus0和consensus1表示利用targeted-phasing-consensus脚本得到的两个单倍体型,不同颜色表示不同的等位HLA基因。未用虚线标注的,表明其结果可通过从头组装的结果(FALCON+FALCON-Unzip结果)得到验证,虚线边框标注的表示通过从头组装结果无法得到验证信息。 |
| Fig. 6 Proposed phasing results of MHC region of HCC27 |
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