早产相关基因的挖掘与特征分析
刘玄石,李巍

Mining and characterization of preterm birth related genes
Liu Xuanshi,Li Wei
表1 筛选出的基因列表中排前5%的早产相关基因
Table 1 Top 5% preterm birth related genes after filtering
基因名称 基因ID 基因名全称 有基因记录的文献数量
TNF 11892 Tumor necrosis factor (TNF superfamily, member 2) 156
IL6 6018 Interleukin 6 (Interferon, beta 2) 155
IL1B 5992 Interleukin 1 beta 140
IL8 6025 Interleukin 8 85
NFKB1 7794 Nuclear factor of kappa light polypeptide gene Enhancer in B-cells 1 (p105) 68
COL1A1 2197 Collagen type I alpha 1 chain 68
PTGS2 9605 Prostaglandin-endoperoxide synthase 2
(Prostaglandin G/H synthase and cyclooxygenase)
63
TLR4 11850 Toll-like receptor 4 57
VEGFA 12680 Vascular endothelial growth factor A 57
IL10 5962 Interleukin 10 53
MT-RNR2 7471 Mitochondrially encoded 16S RNA 51
INS 6081 Insulin 46
PGR 8910 Progesterone receptor 42
IGF1 5464 Insulin-like growth factor 1 (Somatomedin C) 39
TGFB1 11766 Transforming growth factor beta 1 39
SFTPD 10803 Surfactant, pulmonary-associated protein D 38
MMP9 7176 Matrix metallopeptidase 9
(Gelatinase B, 92kDa gelatinase, 92 kDa type IV collagenase)
36
NR3C1 7978 Nuclear receptor subfamily 3, group C, member 1 (Glucocorticoid receptor) 35
SFTPA2B 23441 Surfactant, pulmonary-associated protein A2B 34
IL1A 5991 Interleukin 1 alpha 33