Bmal1对小鼠胚胎期皮层神经元放射状迁移和轴突投射的影响

李芳,黄青芸,刘斯佳,郭忠信,熊欣欣,桂林,束会娟,黄绍明,谭国鹤,刘媛媛

The role of Bmal1 in neuronal radial migration and axonal projection of the embryonic mouse cerebral cortex

Li Fang,Huang Qingyun,Liu Sijia,Guo Zhongxin,Xiong Xinxin,Gui Lin,Shu Huijuan,Huang Shaoming,Tan Guohe,Liu Yuanyuan

图4 Bmal1基因表达下调对P3期皮层神经元放射状迁移的影响 A：子宫内胚胎电转实验观察敲减Bmal1对P3小鼠神经元迁移的影响(标尺=125 μm);B：每个区域中 GFP 阳性细胞所占总阳性细胞百分比的统计图。每组样本数量n=3,结果以平均值±S.E.M表示。

Fig. 4 Effects of down-regulation of Bmal1 expression on radial migration of cortical neurons in the P3 stage