MKL1基因多态性与高原环境适应性的遗传关联研究

张晴,平杰,张昊翔,康波,李元丰,周钢桥

Genetic association of MKL1 gene polymorphisms with the high-altitude adaptation

Zhang Qing,Ping Jie,Zhang Haoxiang,Kang Bo, ,Zhou Gangqiao

表2 在藏族和汉族人群中rs59098711位点的基因型和等位基因型频率分布

Table 2 Distributions of the genotypes and alleles frequencies of rs59098711 in Tibetans and Hans population

基因型 等位基因型 CC TC TT C T 藏族[例(%)] 237(39.83) 253(42.52) 105(17.65) 727(61.09) 463(38.91) 汉族[例(%)] 60(13.57) 214(48.42) 168(38.01) 334(37.78) 550(62.22) OR(95% CI) 3.34(2.40~4.66) 6.32(4.40~9.08) 2.59(2.16~3.09) χ2 50.71 99.56 109.36 P 1.07×10-12 1.90×10-23 1.35×10-25