HPV阳性口咽癌患者预后与T细胞浸润和新抗原负荷相关性分析

卢涣滋,王迪侃,王智

Correlation analysis of the prognosis of HPV positive oropharyngeal cancer patients with T cell infiltration and neoantigen load

Lu Huanzi,Wang Dikan,Wang Zhi

表1 TCGA数据库中HPV+和HPV-口咽癌患者的临床资料和病理学资料

Table 1 Clinical and pathological data of HPV+ and HPV- oropharyngeal cancer patients in the TCGA database

患者信息 HPV+ (n=33) HPV- (n=47) P值 年龄(岁,均值) 55.58 56.34 0.698 性别(女/男) 3/30 9/38 0.215 吸烟史(无/有) 15/18 21/26 0.945 饮酒史(无/有) 10/23 7/40 0.097 部位(扁桃体/舌根/口咽) 22/10/1 23/16/8 0.103 T分期(1/2/3/4) 7/18/3/5 9/16/16/6 0.068 N分期(0/1/2/3) 7/4/21/1 12/6/25/4 0.692 AJCC分期(I/II/III/IV) 3/5/4/21 3/6/9/29 0.833 淋巴血管侵犯(无/有) 25/8 40/7 0.292