HPV阳性口咽癌患者预后与T细胞浸润和新抗原负荷相关性分析
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卢涣滋,王迪侃,王智
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Correlation analysis of the prognosis of HPV positive oropharyngeal cancer patients with T cell infiltration and neoantigen load
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Lu Huanzi,Wang Dikan,Wang Zhi
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| 表3 TCGA数据库口咽癌患者队列的单因素和多因素预后分析 |
| Table 3 Univariate and multivariate prognostic analysis of oropharyngeal cancer patients in the TCGA database |
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| 危险因素 | 单因素预后分析(Log-rank分析) | 多因素预后分析(Cox回归分析) | | HR | P值 | HR | P值 | | 年龄(>60岁vs. <60岁) | 7.906 | <0.001*** | 7.190 | <0.001*** | | 性别(男vs.女) | 0.541 | 0.279 | | | | 吸烟史(有vs.无) | 0.876 | 0.775 | | | | 饮酒史(有vs.无) | 1.310 | 0.633 | | | | 部位(舌根vs.扁桃体) | 0.309 | 0.104 | | | | 部位(口咽vs.扁桃体) | 0.733 | 0.646 | | | | T分期(T3/4 vs. T1/2) | 1.087 | 0.855 | | | | N分期(N2/3 vs. N0/1) | 2.232 | 0.122 | | | | AJCC分期(Ⅲ/Ⅳ vs.Ⅰ/Ⅱ) | 1.207 | 0.744 | | | | 淋巴血管侵犯(有vs.无) | 1.455 | 0.513 | | | | HPV (阳性vs.阴性) | 0.302 | 0.036* | 0.352 | 0.100 |
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