基于结直肠癌细胞系MIC50相关基因对的基础耐药 评分模型构建

陈湖星, 徐蕾, 李静, 郭政, 敖露

The development of a general drug resistance score model based on MIC50 related gene pairs in colorectal cancer cell lines

Chen Huxing, Xu Lei, Li Jing, Guo Zheng, Ao Lu

表5 基础耐药性水平与样本响应信息的相关性评价

Table 5 The correlation between general drug resistance level and drug response information of samples

数据集 样本数 低分组响应率 高分组响应率 P值 GSE72968 68 84% (21/25) 37.2% (16/43) 0.00019 GSE72969 28 71.4% (10/14) 28.5% (4/14) 0.02334 GSE28702 56 76% (19/25) 38.7% (12/31) 0.00526