慢性阻塞性肺疾病全基因组关联研究进展
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钱国清
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Advances in genome-wide association study of chronic obstructive pulmonary disease
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Qian Guoqing
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表4 欧洲人群与中国人群7个作用方向一致的变异位点
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Table 4 Seven variants showing similar effect(s) on COPD in European and Chinese populations
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| 性状 | 基因 | SNP名称 | P值 | | FEV1/FVC | MFAP2* | rs138641402 | 1.00E-04 | | FEV1/FVC | LOC101929516 (intron) * | rs2070600 | 1.12E-04 | | FEV1/FVC | CDC7/TGFBR3* | rs2045517 | 7.71E-04 | | FVC | SPAG17/TBX15* | rs7713065 | 6.39E-03 | | FEV1/FVC | TGFB2* | rs993925 | 1.49E-02 | | FEV1/FVC | CHRM3 (intron) * | rs4237643 | 2.62E-02 | | FEV1 | TNS1* | rs2283847 | 2.82E-02 |
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