猪耳成纤维细胞转录组异质性及对核移植胚胎发育的潜在影响
周俊, 赵成成, 吴霄, 石俊松, 周荣, 吴珍芳, 李紫聪

Transcriptome heterogeneity of porcine ear fibroblast and its potential influence on embryo development in nuclear transplantation
Zhou Jun, Zhao Chengcheng, Wu Xiao, Shi Junsong, Zhou Rong, Wu Zhenfang, Li Zicong
表2 D11_1前50个差异最显著的基因信息
Table 2 Profiles of the top 50 genes with the most significant differences in D11_1
基因 基因全称 表达情况
TMEM198 Transmembrane protein 198 ↑
ALDOB Aldolase, fructose-bisphosphate B ↑
UMOD Uromodulin ↑
ASS1 Argininosuccinate synthase 1 ↑
SLC5A12 Solute carrier family 5 member 12 ↑
SLC34A1 Sus scrofa solute carrier family 34 member 1 (SLC34A1), mRNA ↑
AGR2 Anterior gradient protein 2 homolog precursor ↑
U6 U6 spliceosomal RNA ↑
BHMT Betaine-homocysteine S-methyltransferase 1 ↑
DDC Dopa decarboxylase ↑
DAO D-amino-acid oxidase ↑
SLC13A3 Solute carrier family 13 member 3 ↑
CDH16 Cadherin 16 ↑
CYP2D25 Vitamin D(3) 25-hydroxylase ↑
PPARGC1B PPARG coactivator 1 beta ↑
FBP1 Fructose-1,6-bisphosphatase 1 ↑
G6PC Glucose-6-phosphatase ↑
CLDN2 Claudin-2 ↑
DMGDH Dimethylglycine dehydrogenase ↑
FMO1 Dimethylaniline monooxygenase [N-oxide-forming] 1 ↑
UPP2 Uridine phosphorylase 2 ↑
CYP4A24 Sus scrofa cytochrome P450,family 4,subfamily A,polypeptide 21 (CYP4A21), mRNA ↑
HNF4A Hepatocyte nuclear factor 4-alpha ↑
ADSL Adenylosuccinate lyase ↓
IGFBP6 Insulin-like growth factor-binding protein 6 precursor ↓
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 ↓
MRPS35 Mitochondrial ribosomal protein S35 ↓
TM7SF3 Transmembrane 7 superfamily member 3 ↓
DERA Deoxyribose-phosphate aldolase ↓
LTBR Tumor necrosis factor receptor superfamily member 3 precursor ↓
TULP3 Tubby like protein 3 ↓
PPHLN1 Periphilin 1 ↓
PUS7L Pseudouridylate synthase 7 like ↓
SLC38A1 Solute carrier family 38 member 1 ↓
NEDD1 Neural precursor cell expressed, developmentally down-regulated 1 ↓
SELENOO Sus scrofa selenoprotein O (SELENOO), mRNA ↓
SLC35B3 Solute carrier family 35 member B3 ↓
FAM8A1 Family with sequence similarity 8 member A1 ↓
MBOAT1 Membrane bound O-acyltransferase domain containing 1 ↓
novel gene Lysosomal thioesterase PPT2 precursor ↓
MAN2A2 Mannosidase alpha class 2A member 2 ↓
HMG20A High mobility group 20A ↓
CSPG4 Chondroitin sulfate proteoglycan 4 ↓
SRP54 Signal recognition particle 54 ↓
FOS Proto-oncogene c-Fos ↓
SPTLC2 Serine palmitoyltransferase long chain base subunit 2 ↓
ATXN3 Ataxin-3 ↓