49AISNP：东亚北方三个族群遗传来源推断

郭晓媛, 孙昌春, 薛思瑶, 赵慧, 江丽, 李彩霞

49AISNP: a study on the ancestry inference of the three ethnic groups in the north of East Asia

Guo Xiaoyuan, Sun Changchun, Xue Siyao, Zhao Hui, Jiang Li, Li Caixia

附表1 428AISNP位点信息

Supplementary Table 1 Information of the 428AISNP

序号 rs号 染色体 第37版序列位置 等位基因 Fst值 序号 rs号 染色体 第37版序列位置 等位基因 Fst值 1 rs10018432 4 189437086 C/A 0.0460 40 rs10957985 8 81789921 G/A 0.0645 2 rs10058739 5 144074365 G/A 0.0297 41 rs10972006 9 3430684 T/C 0.0266 3 rs10088365 8 10097398 G/A 0.2709 42 rs10973829 9 38446392 C/T 0.0781 4 rs1009544 22 42239348 G/C 0.0430 43 rs10991718 9 93716118 T/C 0.0048 5 rs10107492 8 80568935 T/A/C 0.0503 44 rs11012716 10 21762267 A/G 0.0302 6 rs10110194 8 119479124 G/C/T 0.0585 45 rs11023463 11 15209506 A/C 0.0052 7 rs10132336 14 74869017 A/G 0.0327 46 rs11032331 11 33678161 G/T 0.0519 8 rs10132483 14 102299420 T/C 0.0519 47 rs11034709 11 38428289 A/G 0.1083 9 rs10134903 14 95229777 G/A 0.0360 48 rs11042911 11 10678785 T/C 0.0432 10 rs10139575 14 57087118 A/C/G 0.0342 49 rs11058961 12 127544998 G/A 0.0438 11 rs10166397 2 44372909 G/T 0.0490 50 rs11086012 19 16032643 A/C 0.0537 12 rs10171891 2 195971878 C/T 0.0431 51 rs11104947 12 88942980 G/A 0.0782 13 rs10177273 2 122239287 C/G 0.0782 52 rs1111212 2 159312733 C/G/T -0.0007 14 rs1026975 4 113971374 T/G 0.0229 53 rs11128125 3 69389614 T/A/C/G 0.0035 15 rs10277413 7 55238464 T/A/G 0.0294 54 rs11133144 4 177229719 A/C/T 0.0446 16 rs10431079 11 116440678 A/G 0.0728 55 rs11151527 18 67347133 A/G 0.0506 17 rs10459664 15 35064934 C/T 0.0505 56 rs11159882 14 89525994 G/T 0.0479 18 rs10483991 14 88682616 G/A 0.0607 57 rs11161614 1 85898160 T/G 0.0299 19 rs10486260 7 8859616 C/T 0.0210 58 rs11164354 1 102439329 G/A 0.0436 20 rs10489744 1 165380623 G/A 0.0690 59 rs11174261 12 62362843 C/T 0.0473 21 rs10506294 12 51070554 T/C 0.0019 60 rs11177698 12 69906287 A/G 0.0534 22 rs10506725 12 77449514 T/C 0.0444 61 rs11222851 11 131831335 G/A 0.0683 23 rs10521076 9 108878562 C/T 0.0775 62 rs11223550 11 133532372 A/G 0.0527 24 rs10756234 9 11316481 C/T -0.0004 63 rs11224765 11 101310590 C/T 0.0981 25 rs10768017 11 33681025 G/T 0.0571 64 rs11257349 10 6260717 T/G 0.0065 26 rs10771923 12 32320912 C/T 0.0332 65 rs1125832 16 52421140 T/A 0.0337 27 rs10778125 12 101962634 C/A 0.0513 66 rs11466640 4 38778903 G/A/T 0.0090 28 rs10806975 6 23766367 A/G/T 0.0372 67 rs11611033 12 63771136 C/T 0.0488 29 rs10819066 9 101356091 C/G 0.0262 68 rs11621121 14 65822493 C/T 0.0990 30 rs10833071 11 19209050 T/C 0.0328 69 rs11625485 14 80242132 T/C 0.0538 31 rs10836092 11 33676946 G/A/C 0.0515 70 rs11625876 14 35248467 C/T 0.0559 32 rs10836093 11 33678526 A/G 0.0530 71 rs11680024 2 49535856 A/C -0.0040 33 rs10847616 12 128910954 A/C/T 0.0308 72 rs1178148 7 18778113 A/C 0.0795 34 rs10849181 12 638166 C/T 0.0525 73 rs11841589 13 73814891 G/T 0.0862 35 rs10858883 12 89893348 T/C -0.0004 74 rs11846710 14 58343352 G/A 0.0768 36 rs10883736 10 104320029 G/T 0.0365 75 rs11847263 14 65775695 T/A/G 0.0635 37 rs10890510 1 48334490 A/C 0.0495 76 rs11874960 18 1948608 A/C/G/T 0.0049 38 rs10894034 11 129255618 C/T 0.0521 77 rs11959012 5 167668843 C/T 0.0694 39 rs10894724 11 133547942 T/A/G 0.0812 78 rs12006467 9 35090720 T/C 0.0993 79 rs12039715 1 242801261 G/C 0.1726 119 rs1391099 4 143373910 A/G/T 0.0025 80 rs12045644 1 40084488 G/T 0.0393 120 rs1420288 16 54477881 T/C 0.0519 81 rs12095503 1 171653329 C/T 0.0346 121 rs1420528 16 52417241 C/G 0.0374 82 rs12134013 1 164459913 C/T 0.0586 122 rs1420638 3 181497374 G/A 0.0407 83 rs12141436 1 68463212 G/A 0.0418 123 rs1422931 5 167397540 C/T 0.0462 84 rs12151767 2 198274929 G/A 0.0548 124 rs1428150 5 132490807 A/G 0.0666 85 rs12231617 12 124930127 C/G 0.0458 125 rs1442502 1 166548317 G/A 0.0277 86 rs12351269 9 16806521 T/C 0.0558 126 rs1453054 2 181359907 T/C/G 0.0119 87 rs12459941 19 10666112 G/A 0.0631 127 rs1465306 7 66699784 T/C 0.0672 88 rs12483769 22 47790072 T/C 0.0870 128 rs1465759 2 142576915 T/C 0.0365 89 rs12488690 3 150490463 G/A 0.0502 129 rs1488485 3 7951364 T/C 0.0125 90 rs12522710 5 65051804 G/A 0.0125 130 rs1522340 3 70369504 G/A 0.0320 91 rs1256519 14 65736324 G/A 0.1027 131 rs1524930 21 40968460 A/G 0.0649 92 rs1256520 14 65737193 C/A 0.0958 132 rs1537523 9 3649097 A/C 0.0512 93 rs12567990 1 207681685 C/T -0.0038 133 rs1538374 10 72718336 G/A 0.0663 94 rs12571942 10 127954919 G/A 0.0056 134 rs1551653 8 34324240 A/G 0.0084 95 rs12586912 14 34023334 G/T 0.0422 135 rs155872 3 1454063 C/T 0.0227 96 rs12588061 14 50481926 T/C 0.0703 136 rs1561201 18 38205375 G/A 0.0330 97 rs12589835 14 30848932 C/T 0.0615 137 rs1566857 4 46048880 A/T 0.0468 98 rs12598852 16 13329469 G/A 0.0500 138 rs160539 16 63353953 C/G 0.0641 99 rs12630087 3 80935171 T/C 0.0429 139 rs1609763 5 142018424 T/G 0.0232 100 rs12632233 3 94033744 G/T 0.0334 140 rs1613215 3 77738317 T/C 0.0509 101 rs12676684 8 118857704 G/C/T 0.0584 141 rs1652519 15 58612113 G/A/C 0.0219 102 rs12691557 2 141469911 G/A/T 0.0461 142 rs1678537 12 57900341 G/A 0.0885 103 rs12768145 10 17610277 G/A 0.0532 143 rs16834705 2 193385209 A/G 0.0168 104 rs12776442 10 59297413 A/G 0.0075 144 rs16850913 2 166421763 A/G 0.0450 105 rs1284605 12 57921188 C/T 0.0863 145 rs16862627 3 150114701 G/A -0.0022 106 rs13076655 3 80920612 C/T 0.0412 146 rs16893074 5 24074021 T/A 0.0042 107 rs13094402 3 80710455 A/G 0.0467 147 rs16895073 5 65596821 T/C 0.0302 108 rs13160399 5 165711426 G/A 0.0550 148 rs16944149 17 10938783 T/G 0.0223 109 rs1317548 10 12245520 G/A 0.0575 149 rs16951472 13 97073977 C/T 0.0503 110 rs131864 22 47271217 T/G 0.0450 150 rs16986850 20 41048928 T/C 0.0307 111 rs1322944 13 53683163 A/G 0.0740 151 rs16991180 20 10148468 G/A 0.0655 112 rs13249584 8 9710943 A/G 0.0786 152 rs16997770 4 124693346 T/C 0.0611 113 rs1325192 1 199244248 G/C/T 0.0625 153 rs17002737 22 42282012 C/T 0.0454 114 rs1333099 13 73691236 G/A 0.0715 154 rs17016175 4 143391299 A/G 0.0018 115 rs13419695 2 7347211 A/T 0.0808 155 rs17029405 3 32451697 C/A 0.0508 116 rs1362553 16 52438954 C/G 0.0329 156 rs17034099 3 11220006 C/A 0.0412 117 rs1371566 2 119738187 T/G 0.0337 157 rs17072984 18 62051788 G/A 0.0312 118 rs1378365 4 61775645 G/A 0.0587 158 rs17076328 5 173143508 G/A 0.0164 159 rs17121800 10 108710873 C/T 0.1007 199 rs2175743 1 70295901 C/T 0.0413 160 rs17129041 1 66996037 T/C 0.0529 200 rs2194757 2 21706029 G/A 0.0108 161 rs17207681 5 138168527 A/G 0.0823 201 rs2195856 1 187922876 A/C 0.0548 162 rs17239258 4 183263055 A/G 0.0500 202 rs2253974 21 23231832 C/T 0.0187 163 rs17372695 4 155060317 A/G -0.0030 203 rs2255957 22 42241372 G/A/T 0.0440 164 rs17377643 22 42152988 A/C 0.0565 204 rs2269275 5 83261405 A/G 0.0688 165 rs17451739 5 144030993 C/T 0.0732 205 rs2269658 22 42280618 T/C 0.0375 166 rs174520 14 88006776 T/G 0.0899 206 rs2278339 18 50866195 T/G 0.0298 167 rs174534 11 61549458 A/G -0.0023 207 rs229562 22 37599065 G/T 0.0827 168 rs174583 11 61609750 C/T -0.0046 208 rs2295756 11 35241229 T/C 0.0000 169 rs17469810 3 80807568 G/A 0.0390 209 rs2313427 16 8815000 G/A 0.0470 170 rs17582830 4 38867427 A/G 0.0004 210 rs2330015 22 22536956 C/T 0.0678 171 rs17583068 4 38908616 G/C/T 0.0558 211 rs2333656 17 58184540 T/C 0.0576 172 rs17599827 5 89518433 A/C 0.0810 212 rs2349093 12 128520953 T/A 0.0004 173 rs17631488 5 18777746 A/G 0.1030 213 rs2352181 10 87653766 G/A 0.0257 174 rs17717717 3 71404405 G/A 0.0320 214 rs2353686 16 86354605 T/C 0.0566 175 rs17766621 14 71262932 T/C 0.0349 215 rs2377962 18 9101722 G/T 0.0522 176 rs17823795 14 63384260 G/A 0.0411 216 rs2430184 1 187786661 G/T 0.0482 177 rs1794072 11 61303803 C/T 0.0446 217 rs2526371 17 56443545 G/A 0.0501 178 rs1795704 12 58739693 C/A 0.0502 218 rs2547353 19 58582797 G/C/T 0.0666 179 rs1835298 11 112057620 G/A 0.0428 219 rs255630 5 127677188 T/C 0.0133 180 rs1841305 18 50163950 A/T 0.0556 220 rs258728 7 81663275 C/A 0.0337 181 rs1861693 12 107603157 C/T 0.0471 221 rs2587694 2 120213497 A/G 0.0026 182 rs1864307 18 57332158 T/G 0.0440 222 rs2589787 5 38260303 G/A 0.0374 183 rs1875174 10 2971488 C/G/T 0.0806 223 rs2622637 8 106505971 G/A/T 0.0951 184 rs1877696 8 9712822 C/G/T 0.0956 224 rs2642066 17 65639014 G/T 0.0910 185 rs189062 2 137349278 G/A 0.0429 225 rs2645645 4 77859067 A/G/T 0.0469 186 rs1898227 16 63282080 A/G/T 0.0546 226 rs26461 5 11202649 C/T 0.0211 187 rs1901786 3 130021945 G/A 0.0411 227 rs27061 5 1362793 T/C 0.0761 188 rs1944975 18 57276748 T/C 0.0369 228 rs2770310 6 70165296 C/A/T 0.0924 189 rs1981370 18 74070815 A/G 0.0722 229 rs2793438 6 24461427 G/C 0.0382 190 rs198464 11 61521621 G/A -0.0050 230 rs2836749 21 40287238 A/C/T 0.0548 191 rs2008819 7 39662268 C/T 0.0459 231 rs2837352 21 41363778 C/T 0.0312 192 rs2011071 5 88741077 A/G 0.0583 232 rs2838408 21 45246422 A/G 0.0750 193 rs2035023 4 137753683 T/C 0.0549 233 rs2853668 5 1300025 G/T 0.0580 194 rs2047297 4 121511851 G/C/T 0.0271 234 rs2901142 2 124764392 C/T 0.0727 195 rs2068746 17 11389480 T/C 0.0464 235 rs2945733 8 134615750 T/G 0.0602 196 rs2099563 3 80740366 G/A 0.0447 236 rs2972336 5 76504150 G/C -0.0028 197 rs2160913 18 8716090 A/C/G 0.0216 237 rs2976396 8 143764001 G/A 0.1521 198 rs2174739 6 79659170 A/G 0.0042 238 rs3027238 17 8135061 T/C 0.9803 239 rs3104517 15 27940339 A/G 0.0288 279 rs4690508 4 178295766 G/T 0.0504 240 rs3111745 3 21827159 G/T 0.0751 280 rs4718412 7 66286867 T/C 0.0751 241 rs315808 5 169750158 G/T 0.0626 281 rs475235 18 10029988 G/A/T 0.0289 242 rs3217805 12 4388084 C/A/G/T 0.0844 282 rs4756305 11 36292065 T/A/C 0.0532 243 rs321967 7 78314549 G/A/C 0.0454 283 rs4790409 17 1243941 C/T 0.0600 244 rs34052939 3 80765431 C/G/T 0.0447 284 rs480631 6 138406328 C/A/T 0.0620 245 rs34254286 4 164411734 A/G 0 285 rs4820428 22 41537589 A/G 0.0762 246 rs374722 2 147839830 G/A 0.0740 286 rs4834226 4 128986874 C/T -0.0008 247 rs3757419 7 66029429 C/T 0.0718 287 rs4839523 1 116800016 T/C 0.0284 248 rs3757425 7 150067640 A/C 0.0706 288 rs4846992 1 230137518 A/G 0.0426 249 rs3758229 9 95078852 C/A/G 0.0574 289 rs4865142 4 57549583 C/T 0.0372 250 rs3775539 4 99304600 A/G 0.0452 290 rs4865290 4 53278689 G/A 0.0307 251 rs3910142 20 12921966 T/C 0.0613 291 rs4883926 13 73843655 T/C 0.0583 252 rs3923084 2 227948726 A/G/T 0.0586 292 rs4902391 14 65815979 G/T 0.0929 253 rs3923736 7 155060730 A/C/G/T 0.0714 293 rs4903754 14 40865770 G/A 0.0492 254 rs3924308 9 130185385 C/A 0.0129 294 rs4912933 5 143038150 G/A/C/T -0.0034 255 rs4133446 5 86155113 T/C 0.0645 295 rs4918000 10 94837743 C/T 0.0399 256 rs4144800 4 38006916 G/A 0.0228 296 rs4922234 8 16639271 G/A/C/T 0.0433 257 rs4254643 3 792207 G/A 0.0307 297 rs4938285 11 116440011 T/C 0.0697 258 rs4263026 18 73309989 G/C 0.0466 298 rs5022079 18 76478188 A/G 0.0931 259 rs4280278 16 29439227 C/G 0.0841 299 rs5030883 10 70480868 A/C/T 0.0759 260 rs4325622 17 28526475 T/C 0.3617 300 rs520605 1 184795779 C/T 0.0581 261 rs4328700 20 23709545 A/G 0.0344 301 rs536430 10 79001643 C/T 0.0107 262 rs4353835 3 32446775 C/T 0.0849 302 rs5770018 22 49595560 C/T 0.0411 263 rs4355871 9 29653331 G/A/C 0.0665 303 rs5996064 22 42172080 C/T 0.0476 264 rs4372441 11 7657259 C/T 0.0787 304 rs6000401 22 37149336 C/T 0.0426 265 rs4393669 18 67296561 T/C 0.0330 305 rs6007756 22 48282309 G/A/C 0.0571 266 rs4414069 1 200391561 T/C 0.0478 306 rs6016226 20 38661387 C/T 0.0181 267 rs4466495 9 17496114 C/A/T 0.0489 307 rs6030932 20 42146320 T/G 0.0659 268 rs4486887 16 50677571 C/T 0.0579 308 rs6031579 20 43015108 C/G 0.0654 269 rs4491175 11 90956214 T/C 0.0485 309 rs6049064 20 23727145 C/T 0.0360 270 rs4533076 12 56069231 C/A 0.0410 310 rs6074520 20 12905188 T/A/C 0.0559 271 rs4543050 3 74954560 A/C/T 0.0194 311 rs6117562 20 753310 G/A -0.0011 272 rs4578397 11 131832284 G/T 0.0737 312 rs6123723 20 37082145 C/T 0.0891 273 rs4603782 2 102735809 T/A 0.0642 313 rs6137010 20 2090118 C/T 0.0110 274 rs4668680 2 10529961 A/G 0.0199 314 rs6138046 20 23704388 G/C/T 0.0342 275 rs4674759 2 224068666 G/A 0.0059 315 rs616022 3 80711349 G/C/T 0.0253 276 rs4677399 3 74519384 T/C 0.0307 316 rs6436971 2 231582797 T/C 0.0815 277 rs4678169 3 124543103 C/A 0.0557 317 rs6450876 5 31925423 A/G -0.0024 278 rs4681869 3 58573534 C/T 0.0583 318 rs6465469 7 95179593 G/A 0.0611 319 rs6478966 9 101776125 G/A 0.0192 359 rs760873 20 45393072 T/G 0.0582 320 rs6502840 17 4989857 C/T 0.0515 360 rs7630111 3 114165901 C/A 0.0499 321 rs6549596 3 74507710 T/C 0.0271 361 rs7642488 3 84688723 C/T 0.0406 322 rs6549601 3 74525187 C/T 0.0307 362 rs7655849 4 161867415 T/A 0.0759 323 rs6559935 9 89140339 G/A 0.0425 363 rs7666030 4 24728480 G/A 0.0492 324 rs6561294 13 46695350 T/C 0.0215 364 rs7674135 4 84577025 T/C 0.0399 325 rs6576127 14 106194763 C/T 0.1076 365 rs769411 2 171693639 C/G/T 0.0537 326 rs6589072 11 109322914 C/G 0.0501 366 rs7698051 4 60278484 A/G 0.0445 327 rs6599390 4 956047 A/G 0.0584 367 rs770576 11 99884272 A/G 0.0565 328 rs6707773 2 191344132 C/T 0.0279 368 rs7802058 7 81697666 A/C 0.0512 329 rs6717406 2 187743228 T/G 0.0326 369 rs7845383 8 88289450 G/T 0.0361 330 rs6738590 2 65059603 A/G 0.0429 370 rs789378 3 154079645 C/T 0.0205 331 rs6743998 2 196676489 T/A/C/G 0.0612 371 rs8014475 14 65811537 T/C 0.0937 332 rs6760967 2 4669324 C/T 0.0400 372 rs8015594 14 40942142 C/G 0.0688 333 rs6767410 3 80699208 C/T 0.0505 373 rs8049660 16 89857700 A/G 0.0398 334 rs6768622 3 74508075 C/T 0.0271 374 rs8050932 16 50687673 C/T 0.0545 335 rs6833150 4 61659236 A/G 0.0235 375 rs8060207 16 82273372 G/A 0.0287 336 rs6898653 5 115975656 A/G 0.0654 376 rs807959 19 22115835 A/G 0.0561 337 rs6924957 6 96853579 G/T 0.0527 377 rs8084884 18 75513922 A/T 0.0597 338 rs6955018 7 125115418 A/G 0.0474 378 rs8107011 19 30841000 A/C 0.0341 339 rs7006443 8 9290753 T/C 0.0383 379 rs827287 10 72708276 A/T 0.0435 340 rs7022178 9 29780195 G/A 0.0720 380 rs883433 19 39206288 C/T 0.0580 341 rs7032231 9 117025771 C/A 0.0706 381 rs928844 21 37999799 C/T 0.0846 342 rs7038964 9 104423907 C/T 0.0419 382 rs929115 1 171591189 T/G 0.0757 343 rs7097617 10 77504287 A/G 0.0447 383 rs9302550 16 52405521 C/T 0.0374 344 rs7117447 11 101351383 G/A 0.1118 384 rs9303660 17 31420730 C/T 0.0614 345 rs712645 5 110585627 C/T 0.0604 385 rs9321180 6 130102959 C/T 0.0866 346 rs713278 11 133563491 G/A 0.0619 386 rs933199 6 26112893 T/C 0.0107 347 rs7173716 15 70123826 T/G 0.0723 387 rs9384981 6 116803328 T/C 0.0259 348 rs7173982 15 36685718 C/A/T -0.0013 388 rs9398434 6 116787017 T/G 0.0229 349 rs7193505 16 52401477 C/G 0.0394 389 rs943327 9 113599422 T/C 0.0695 350 rs7195477 16 29288634 T/C 0.0020 390 rs9532080 13 38126537 G/A 0.0395 351 rs7211426 17 53654548 G/A/C 0.0037 391 rs9549212 13 41022093 C/T 0.0708 352 rs7268940 20 9961532 C/T 0.0461 392 rs9590216 13 95905305 T/C -0.0035 353 rs7271913 20 39263421 C/A 0.0155 393 rs9663367 10 19776910 A/C/T 0.0370 354 rs7317643 13 108536028 C/T 0.1665 394 rs978605 10 94903693 A/G 0.0208 355 rs738745 22 48246398 A/G 0.0255 395 rs9825713 3 100936248 C/A 0.0450 356 rs741245 12 4227248 G/A 0.0535 396 rs9826148 3 114464858 C/A/T 0.0677 357 rs7555405 1 31183486 C/T 0.0420 397 rs9852677 3 50291617 G/A/T 0.0412 358 rs758219 19 40294953 T/C 0.0461 398 rs9857773 3 149344615 C/A 0.0547 399 rs9860483 3 138730737 C/T 0.0985 414 rs1991955 6 29884066 A/C 0.0938 400 rs9896443 17 47125982 T/C 0.0738 415 rs2182268 13 113170683 G/A 0.0573 401 rs9941426 18 487281 T/G 0.0689 416 rs2261033 6 31603591 A/G 0.1538 402 rs9947737 18 455128 A/G 0.0477 417 rs2524095 6 31266117 A/C 0.0456 403 rs9979724 21 22447717 A/G 0.0383 418 rs284784 4 100335874 C/A 0.0255 404 rs10901244 9 136079463 C/T 0.0077 419 rs3015224 9 72728388 A/G 0.1419 405 rs11078951 17 38831415 T/A/G 0.1249 420 rs3130688 6 31210216 C/A/T 0.0991 406 rs11673276 19 55347963 C/T 0.0264 421 rs3135402 6 33024654 A/C 0.1028 407 rs12896399 14 92773663 G/T 0.0615 422 rs376877 6 33024606 C/G 0.0902 408 rs1414241 9 21744392 G/A/T 0.0756 423 rs4800105 18 19651982 C/G/T 0.0906 409 rs1431403 6 33047031 T/C -0.0048 424 rs5758649 22 42605548 C/T 0.0059 410 rs1496279 5 18680420 A/T - 425 rs6062275 20 61146909 C/G/T 0.1420 411 rs1500127 5 165739982 C/T 0.0416 426 rs7207346 17 75668619 C/A/G/T 0.0105 412 rs174592 11 61618608 A/G -0.0049 427 rs8074124 17 36531565 C/T 0.0457 413 rs1927568 13 99740117 T/C 0.0137 428 rs901134 3 84688173 G/A 0.0574