An association study between <EM>grin1, bdnf </EM>genes and bipolar disorder

LIU Min, LING Si-Hai, LI Wen-Biao, WANG Chuan-Yue, CHEN Da-Fang, WANG Gang

doi:10.1360/yc-007-0041

[an error occurred while processing this directive]

Hereditas(Beijing) >

2007 , Vol. 29 >Issue 1: 41 - 41―46

DOI: https://doi.org/10.1360/yc-007-0041

研究报告

An association study between grin1, bdnf genes and bipolar disorder

Expand

1. Beijing Anding Hospital Affiliated to the Capital University of Medical Sciences, Beijing 100088, China
2. Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100083, China

Received date: 2006-03-03

Revised date: 2006-08-30

Online published: 2007-01-10

Fold

Abstract

in order to evaluate the role of inherited variation in GRIN1, BDNF genes in human bipolar disorder, a correlation study using 4 single nucleotide polymorphisms with GRIN1, BDNF genes(2 SNPs in every gene respectively) by means of TaqMan was performed in 100 unrelated cases subjects and 50 control subjects. Significant result was obtained that the SNPs in GRIN1 gene are related to the BP(p<0.05 ). But the SNPs in BDNF gene have no statistical significance. The result has proved again that the GRIN1 gene confers susceptibility to bipolar disorder.

Cite this article

LIU Min, LING Si-Hai, LI Wen-Biao, WANG Chuan-Yue, CHEN Da-Fang, WANG Gang . An association study between grin1, bdnf genes and bipolar disorder[J]. Hereditas(Beijing), 2007 , 29(1) : 41 -41―46 . DOI: 10.1360/yc-007-0041

Options

Outlines

〈

〉

www.chinagene.cn
备案号：京ICP备09063187号

模态框（Modal）标题

Abstract

Cite this article