Research progress of zebrafish as a model system for hematological neoplasms

ZHANG Yong, CHEN Fang-Yuan, DENG Min

doi:10.3724/SP.J.1005.2009.00889

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Hereditas(Beijing) >

2009 , Vol. 31 >Issue 9: 889 - 895

DOI: https://doi.org/10.3724/SP.J.1005.2009.00889

综述

Research progress of zebrafish as a model system for hematological neoplasms

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1. Department of Hematology, RenJi Hospital and Laboratory of Leukemia, Shanghai Institute of Hematology, Shanghai Jiao Tong
University School of Medicine, Shanghai 200127, China;
2. Laboratory of Development and Diseases, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China

Received date: 2008-08-27

Revised date: 2009-06-03

Online published: 2009-09-10

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Abstract

Zebrafish is becoming a powerful vertebrate model for studies of human genetics and hematology. The biological characteristics of zebrafish organism, as well as its potential model for human blood developmental biology and hematologic malignancies are discussed. At last, we discussed the prospects of zebrafish in the clinical and basic research of hematological neoplasms.

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ZHANG Yong, CHEN Fang-Yuan, DENG Min . Research progress of zebrafish as a model system for hematological neoplasms[J]. Hereditas(Beijing), 2009 , 31(9) : 889 -895 . DOI: 10.3724/SP.J.1005.2009.00889

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