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Telomere biology of the chicken

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  • College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China

Received date: 2011-04-13

  Revised date: 2011-06-28

  Online published: 2012-01-25

Abstract

Telomeres, the nucleoprotein “caps” protecting the ends of linear chromosomes, are maintained by telomerase. Telomeres have important roles in maintaining genomic stability and preventing senescence or oncogenesis. Chicken is a classical model animal for genetic and developmental studies. With further development of chicken genomics, great progress has been made in research of chicken telomere and telomerase. This review describes recent advances and future research directions in chicken telomere biology.

Cite this article

WANG Wei, WANG Shan-Shan, LI Hui, WANG Ning . Telomere biology of the chicken[J]. Hereditas(Beijing), 2012 , 34(1) : 19 -26 . DOI: 10.3724/SP.J.1005.2012.00019

References

[1] International Chicken Genome Sequencing Consortium (ICGSC). Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature, 2004, 432(7018): 695-716.
[2] Gregory TR, Nicol JA, Tamm H, Kullman B, Kullman K, Leitch IJ, Murray BG, Kapraun DF, Greilhuber J, Bennett MD. Eukaryotic genome size databases. Nucleic Acids Res, 2007, 35(S1): D332-338.
[3] Delany ME, Krupkin AB, Miller MM. Organization of telomere sequences in birds: evidence for arrays of extreme length and for in vivo shortening. Cytogenet Cell Genet, 2000, 90(1-2): 139-145.
[4] Denchi EL, de Lange T. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature, 2007, 448(7157): 1068-1071.
[5] Griffith JD, Comeau L, Rosenfield S, Stansel RM, Bianchi A, Moss H, de Lange T. Mammalian telomeres end in a large duplex loop. Cell, 1999, 97(4): 503-514.
[6] Nikitina T, Woodcock CL. Closed chromatin loops at the ends of chromosomes. J Cell Biol, 2004, 166(2): 161-165.
[7] Wei C, Price CM. Cell cycle localization, dimerization, and binding domain architecture of the telomere protein cPot1. Mol Cell Biol, 2004, 24(5): 2091-2102.
[8] Nanda I, Schrama D, Feichtinger W, Haaf T, Schartl M, Schmid M. Distribution of telomeric (TTAGGG)(n) sequences in avian chromosomes. Chromosoma, 2002, 111(4): 215-227.
[9] Delany ME, Gessaro TM, Rodrigue KL, Daniels LM. Chromosomal mapping of chicken mega-telomere arrays to GGA9, 16, 28 and W using a cytogenomic approach. Cytogenet Genome Res, 2007, 117(1-4): 54-63.
[10] O'Hare TH, Delany ME. Genetic variation exists for telomeric array organization within and among the genomes of normal, immortalized, and transformed chicken systems. Chromosome Res, 2009, 17(8): 947-964.
[11] Rodrigue KL, May BP, Famula TR, Delany ME. Meiotic instability of chicken ultra-long telomeres and mapping of a 2.8 megabase array to the W-sex chromosome. Chromosome Res, 2005, 13(6): 581-591.
[12] de Lange T, Shiue L, Myers RM, Cox DR, Naylor SL, Killery AM, Varmus HE. Structure and variability of human chromosome ends. Mol Cell Biol, 1990, 10(2): 518-527.
[13] Kipling D, Cooke HJ. Hypervariable ultra-long telomeres in mice. Nature, 1990, 347(6291): 400-402.
[14] Swanberg SE, O'Hare TH, Robb EA, Robinson CM, Chang H, Delany ME. Telomere biology of the chicken: a model for aging research. Exp Gerontol, 2010, 45(9): 647-654.
[15] Starling JA, Maule J, Hastie ND, Allshire RC. Extensive telomere repeat arrays in mouse are hypervariable. Nucleic Acids Res, 1990, 18(23): 6881-6888.
[16] de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev, 2005, 19(18): 2100-2110.
[17] De Rycker M, Venkatesan RN, Wei C, Price CM. Vertebrate tankyrase domain structure and sterile alpha motif (SAM)-mediated multimerization. Biochem J, 2003, 372(Pt 1): 87-96.
[18] Konrad JP, Mills W, Easty DJ, Farr CJ. Cloning and characterisation of the chicken gene encoding the telomeric protein TRF2. Gene, 1999, 239(1): 81-90.
[19] Tan M, Wei C, Price CM. The telomeric protein Rap1 is conserved in vertebrates and is expressed from a bidirectional promoter positioned between the Rap1 and KARS genes. Gene, 2003, 323: 1-10.
[20] Bezzubova O, Shinohara A, Mueller RG, Ogawa H, Buerstedde JM. A chicken RAD51 homologue is expressed at high levels in lymphoid and reproductive organs. Nucleic Acids Res, 1993, 21(7): 1577-1580.
[21] De Boeck G, Forsyth RG, Praet M, Hogendoorn PCW. Telomere-associated proteins: cross-talk between telomere maintenance and telomere-lengthening mechanisms. J Pathol, 2009, 217(3): 327-344.
[22] Orelli BJ, Logsdon-Jr JM Jr, Bishop DK. Nine novel conserved motifs in BRCA1 identified by the chicken ort
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