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Progress on the miRNA related with mammary gland development and lactation

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  • Institute of Dairy Science, College of Animal Science, Zhejiang University, Hangzhou 310058, China

Received date: 2012-10-20

  Revised date: 2012-12-30

  Online published: 2013-06-25

Abstract

MicroRNAs (miRNAs) are non-coding RNAs that play important roles in post transcriptional regulation. They are involved in the regulation of mammary gland development and lactation. In this paper, we summarized the expression pattern of miRNAs which varied with tissues and lactation stages, and the functions of several miRNAs are also briefly reviewed. The objective of this work is to give reference for further study on miRNAs in mammary gland, and to provide theoretical basis and ideas for the use of miRNAs in improving healthy development of mammary gland and regulating the efficiency of lactation and the quality of milk.

Cite this article

JIN Xiao-Lu, YANG Jian-Xiang, LI Zhen, LIU Hong-Yun, LIU Jian-Xin . Progress on the miRNA related with mammary gland development and lactation[J]. Hereditas(Beijing), 2013 , 35(6) : 695 -702 . DOI: 10.3724/SP.J.1005.2013.00695

References

[1] Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 1993, 75(5): 843-854.
[2] Wightman B, Ha I, Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell, 1993, 75(5): 855-862.
[3] Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE, Horvitz HR, Ruvkun G. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature, 2000, 403(6772): 901-906.
[4] Hennighausen L, Robinson GW. Information networks in the mammary gland. Nat Rev Mol Cell Biol, 2005, 6(9): 715-725.
[5] Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 2004, 116(2): 281-297.
[6] Liu CG, Calin GA, Meloon B, Gamliel N, Sevignani C, Ferracin M, Dumitru CD, Shimizu M, Zupo S, Dono M, Alder H, Bullrich F, Negrini M, Croce CM. An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues. Proc Natl Acad Sci USA, 2004, 101(26): 9740-9744.
[7] Silveri L, Tilly G, Vilotte JL, Le Provost F. MicroRNA involvement in mammary gland development and breast cancer. Reprod Nutr Dev, 2006, 46(5): 549-556.
[8] Gu ZL, Eleswarapu S, Jiang HL. Identification and characterization of microRNAs from the bovine adipose tissue and mammary gland. FEBS Lett, 2007, 581(5): 981-988.
[9] Sdassi N, Silveri L, Laubier J, Tilly G, Costa J, Layani S, Vilotte JL, Le Provost F. Identification and characterization of new miRNAs cloned from normal mouse mammary gland. BMC Genomics, 2009, 10: 149.
[10] Li Z, Liu HY, Jin XL, Lo LJ, Liu JX. Expression profiles of microRNAs from lactating and non-lactating bovine mammary glands and identification of miRNA related to lactation. BMC Genomics, 2012, 13: 731.
[11] Macias H, Hinck L. Mammary gland development. Wiley Interdiscip Rev Dev Biol, 2012, 1(4): 533-557.
[12] Avril-Sassen S, Goldstein LD, Stingl J, Blenkiron C, Le Quesne J, Spiteri I, Karagavriilidou K, Watson CJ, Tavaré S, Miska EA, Caldas C. Characterisation of microRNA expression in post-natal mouse mammary gland development. BMC Genomics, 2009, 10: 548.
[13] Wang CM, Li QZ. Identification of differentially expressed microRNAs during the development of chinese murine mammary gland. J Genet Genomics, 2007, 34(11): 966-973.
[14] Wang M, Moisá S, Khan MJ, Wang J, Bu D, Loor JJ. MicroRNA expression patterns in the bovine mammary gland are affected by stage of lactation. J Dairy Sci, 2012, 95(11): 6529-6535.
[15] Ji ZB, Wang GZ, Xie ZJ, Wang JM, Zhang CL, Dong F, Chen CX. Identification of novel and differentially ex-pressed microRNAs of dairy goat mammary gland tissues using Solexa sequencing and bioinformatics. PLoS One, 2012, 7(11): e49463.
[16] Boutinaud M, Rulquin H, Keisler DH, Djiane J, Jammes H. Use of somatic cells from goat milk for dynamic studies of gene expression in the mammary gland. J Anim Sci, 2002, 80(5): 1258-1269.
[17] Kosaka N, Izumi H, Sekine K, Ochiya T. microRNA as a new immune-regulatory agent in breast milk. Silence, 2010, 1(1): 7.
[18] 宋雪梅, 姜俊芳, 蒋永清. 哺乳动物乳汁miRNA的研究进展. 遗传, 2012, 34(10): 1233-1241.
[19] Chen X, Gao C, Li HJ, Huang L, Sun Q, Dong YY, Tian CL, Gao SP, Dong HL, Guan DL, Hu XY, Zhao SJ, Li L, Zhu L, Yan Q, Zhang JF, Zen K, Zhang CY. Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products. Cell Res, 2010, 20(10): 1128-1137.
[20] Izumi H, Kosaka N, Shimizu T, Sekine K, Ochiya T, Takase M. Bovine milk contains microRNA and messenger RNA that are stable under degradative conditions. J Dairy Sci, 2012, 95(9): 4831-4841.
[21] Gu YR, Li MZ, Wang T, Liang Y, Zhong ZJ, Wang XY, Zhou Q, Chen L, Lang QL, He ZP, Chen XH, Gong JJ, Gao XL, Li XW, Lv XB. Lactation-related microRNA ex-pression profiles of porcine breast milk exosomes.
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