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Reviews

Advances in porcine miRNAome

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  • 1. College of Animal Science & Technology, Hunan Agricultural University, Changsha 410128, China;
    2. Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Changsha 410128, China;
    3. Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China;
    4. University of the Chinese Academy of Sciences, Beijing 100049, China

Received date: 2014-05-04

  Online published: 2014-10-20

Abstract

MicroRNA (miRNA), a class of non-coding RNA (about 22 nt), widely exists in different organisms and plays an important role in growth, development, and apoptosis. Recently, many studies have shown that miRNAs serve as a regulatory mechanism in mediating the development of pig muscle, fat, reproductive and immunity traits. The next-generation of high-throughput sequencing technology plays a critical role on finding new miRNAs and identifying their different expressions in pig. In this review, we summarize the application of the next-generation of high-throughput sequencing technology in the study of pig miRNAs as well as the regulatory roles of several important miRNAs in fat metabolism, muscle development, oocyte maturation and development of B cells and T cells. This review will provide insight into the research on pig miRNAs, and some ideas on how to improve pork quality, growth, reproductive and immunity performance.

Cite this article

Maoliang Ran, Bin Chen, Jie Yin, Anqi Yang, Zhi Li, Ming Jiang . Advances in porcine miRNAome[J]. Hereditas(Beijing), 2014 , 36(10) : 974 -984 . DOI: 10.3724/SP.J.1005.2014.0974

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