Genetics is one of the core courses for undergraduates majoring in related disciplines. Most universities use general genetics textbooks in teaching, which will lead to different teaching qualities for students in different majors, especially in sericulture, apiculture, plant protection, and animal science. This is especially true for students majoring in insects. Although there are some entomology cases in general textbooks, they have not been updated with developments in entomology and cannot meet the needs of comprehensive quality training. Therefore, we review entomology cases that can be used in genetics courses, introduce genetics teaching points, offers replacements for some non-classical cases in general genetics textbooks, and supplement several cases of insect developmental genetics, extranuclear genetics, and evolutionary genetics, which are seldom described in general genetics textbooks. We also establish a genetics theoretical system and experimental teaching design for entomology-related majors to highlight the characteristics of entomology- related majors in genetics teaching, aiming to help students and teachers in related majors.