Progress on molecular mechanisms of bacterial transcription termination
Received date: 2024-08-21
Revised date: 2024-10-12
Online published: 2024-10-25
Supported by
Supported by the Basic Research Zone Program of Shanghai(JCYJ-SHFY-2022-012);National Key Research and Development Program of China(2018YFA0903701);Strategic Priority Research Program of the CAS(CAS XDB29020000)
Transcription is the process by which genetic information is copied from DNA to RNA, and it can be divided into three stages: transcription initiation, elongation, and termination. Transcription termination is the last step of gene transcription and is crucial for accurate gene expression. Two prevailing modes of transcription termination exist in bacteria: Rho-dependent termination and intrinsic termination (Rho-independent termination). Transcription termination is positively and negatively regulated by bacterial or bacteriophage proteins. In this review, we summarize the research progress of bacterial transcription and its regulation, with the aim of providing a theoretical foundation for further studies and understanding of transcription termination process.
Linlin You, Yu Zhang . Progress on molecular mechanisms of bacterial transcription termination[J]. Hereditas(Beijing), 2024 , 46(12) : 982 -994 . DOI: 10.16288/j.yczz.24-244
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