家畜基因组选择研究进展

doi:10.16288/j.yczz.16-342

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Hereditas(Beijing) ›› 2017, Vol. 39 ›› Issue (5): 377-387.doi: 10.16288/j.yczz.16-342

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The research progress of genomic selection in livestock

Hongwei Li(),Ruijun Wang(),Zhiying Wang,Xuewu Li,Zhenyu Wang,Yanjun Zhang,Rui Su,Zhihong Liu,Jinquan Li()

Inner Mongolia Key Laboratory of Animal Genetics, Breeding and Reproduction, Inner Mongolia Agricultural University, Hohhot 0 10018, China

Received:2016-10-17 Revised:2017-01-15 Online:2017-03-20 Published:2017-12-25
Supported by:
the National High Technology Research and Development Program of China(2013AA102506);the Program of Science and Technology Plan of Inner Mongolia Autonomous Region, the National Natural Science Foundation of China(31560619,31660639);the Key Program of Natural Science Foundation of Inner Mongolia of China(2016ZD02);National Special Fund for Agro-scientific Research in the Public Interest(201303059);the Modern Agricultural Industry Technology System of Ministry of Agriculture of China(CARS-40-05)

Abstract

Abstract:

With the development of gene chip and breeding technology, genomic selection in plants and animals has become research hotspots in recent years. Genomic selection has been extensively applied to all kinds of economic livestock, due to its high accuracy, short generation intervals and low breeding costs. In this review, we summarize genotyping technology and the methods for genomic breeding value estimation, the latter including the least square method, RR-BLUP, GBLUP, ssGBLUP, BayesA and BayesB. We also cover basic principles of genomic selection and compare their genetic marker ranges, genomic selection accuracy and operational speed. In addition, we list common indicators, methods and influencing factors that are related to genomic selection accuracy. Lastly, we discuss latest applications and the current problems of genomic selection at home and abroad. Importantly, we envision future status of genomic selection research, including multi-trait and multi-population genomic selection, as well as impact of whole genome sequencing and dominant effects on genomic selection. This review will provide some venues for other breeders to further understand genome selection.

Key words: genomic selection, genotyping technology, the methods of genomic breeding value estimation

Hongwei Li,Ruijun Wang,Zhiying Wang,Xuewu Li,Zhenyu Wang,Yanjun Zhang,Rui Su,Zhihong Liu,Jinquan Li. The research progress of genomic selection in livestock[J]. Hereditas(Beijing), 2017, 39(5): 377-387.

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