时间生物学—2017年诺贝尔生理或医学奖解读

doi:10.16288/j.yczz.17-397

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Hereditas(Beijing) ›› 2018, Vol. 40 ›› Issue (1): 1-11.doi: 10.16288/j.yczz.17-397

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Chronobiology—2017 Nobel Prize in Physiology or Medicine

Li Yuan,Yirou Li,Xiaodong Xu

Hebei Normal University, College of Life Sciences, Shijiazhuang 050024, China

Received:2017-12-04 Revised:2017-12-22 Online:2018-01-20 Published:2017-12-27
Supported by:
[Supported by the National Natural Science Foundation of China (No. 31570285), Program for New Century Excellent Talents in University (No. NCET-13-0771), Graduate Student Innovation Fund of Hebei Province (No. CXZZBS2017093), and Hebei Normal University Undergraduate Student Training Grant (No. 201710094011)]

Abstract

Abstract:

Chronobiology is a field of biology that examines the generation of biological rhythms in various creatures and in many parts of body, and their adaptive fitness to solar- and lunar-related periodic phenomena. The synchronization of internal circadian clocks with external timing signals confers accurate phase response and tissue homeostasis. Herein we state a series of studies on circadian rhythms and introduce the brief history of chronobiology. We also present a detailed timeline of the discoveries on molecular mechanisms controlling circadian rhythm in Drosophila, which was awarded the 2017 Nobel Prize in Physiology or Medicine. The latest findings and new perspectives are further summarized to indicate the significance of circadian research.

Key words: chronobiology, biological clock, circadian rhythms, tissue homeostasis, fitness

Li Yuan, Yirou Li, Xiaodong Xu. Chronobiology—2017 Nobel Prize in Physiology or Medicine[J]. Hereditas(Beijing), 2018, 40(1): 1-11.

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