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HEREDITAS ›› 2009, Vol. 31 ›› Issue (9): 889-895.doi: 10.3724/SP.J.1005.2009.00889

• 综述 • Previous Articles     Next Articles

Research progress of zebrafish as a model system for hematological neoplasms

ZHANG Yong1;CHEN Fang-Yuan1;DENG Min2

  

  1. 1. Department of Hematology, RenJi Hospital and Laboratory of Leukemia, Shanghai Institute of Hematology, Shanghai Jiao Tong
    University School of Medicine, Shanghai
    200127, China;
    2. Laboratory of Development and Diseases, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China
  • Received:2008-08-27 Revised:2009-06-03 Online:2009-09-10 Published:2009-09-10
  • Contact: ZHANG Yong Zhang

Abstract:

Zebrafish is becoming a powerful vertebrate model for studies of human genetics and hematology. The biological characteristics of zebrafish organism, as well as its potential model for human blood developmental biology and hematologic malignancies are discussed. At last, we discussed the prospects of zebrafish in the clinical and basic research of hematological neoplasms.