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HEREDITAS ›› 2013, Vol. 35 ›› Issue (7): 867-874.doi: 10.3724/SP.J.1005.2013.00867

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Progress on identification and analysis of DNase I hypersensitive sites in plant genomes

ZHANG Tao, YANG Zu-Jun   

  1. School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China
  • Received:2012-12-20 Revised:2013-02-04 Online:2013-07-20 Published:2013-07-25

Abstract: Eukaryotes’s gene expression and regulation relies on the interaction of their cis-acting elements and trans-acting factors. The cis-elements are specific DNA sequences in the genome and frequently located in the untranslated regions. The trans-acting factors are usually considered to be proteins that bind to the cis-acting sequences to regulate gene expression. It is well known that the cis-elements are always associated with DNase I hypersensitive site, which is a signature of open chromatin. The identification of all the functional cis-element using high-throughput method in plant genome has not been initiated in plant genomes. With the rapid achievement of genomics studies, an increasing number of plant genomes have been sequenced. Genome-wide identification of DNase I hypersensitive sites will be a considerably efficient method to locate cis-element in plants, which will provide a vital potential for further plant functional genomics. The present review is to reveal the recent progresses on identification and analysis of DNase I hypersensitive site in plant genomes.

Key words: plant genome, gene expression and regulation, DNase I hypersensitive site