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Hereditas(Beijing) ›› 2019, Vol. 41 ›› Issue (9): 883-892.doi: 10.16288/j.yczz.19-122

• Resource and Platform • Previous Articles    

Current metabolomics platforms: technical composition and applications

Fengxia Zhang,Guodong Wang()   

  1. State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovation Academy of Seed Design, Chinese Academy of Sciences, Beijing 100101, China
  • Received:2019-04-30 Revised:2019-06-30 Online:2019-09-20 Published:2019-08-11
  • Contact: Wang Guodong E-mail:gdwang@genetics.ac.cn
  • Supported by:
    Supported by the State Key Laboratory of Plant Genomics of China Nos(SKLPG2016A-13);Supported by the State Key Laboratory of Plant Genomics of China Nos(SKLPG2016B-13)

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Abstract:

Metabolomics (defined as comprehensive small molecule chemical analysis), together with genomics, transcriptomics, proteomics and phenomics, now plays a fundamental role in system biological studies. Chromatography- mass spectrometry machines, which have the characteristics of high resolution and high sensitivity, are widely used for metabolomics analysis, both qualitatively and quantitatively. With the fast development of the chromatography-mass spectrometry technology, metabolomics analysis has been successfully applied in various biological research fields. Here, we introduce the different chromatography-mass spectrum machines used for metabolomics analysis and their applications to various biological issues by mainly using the metabolomics platform in Institute of Genetics and Developmental Biology as a case study.

Key words: small molecule chemicals, metabolomics platform, chromatography-mass spectrometry, system biology