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HEREDITAS ›› 1991, Vol. 18 ›› Issue (3): 200-207.

• 论文 • Previous Articles     Next Articles

The Application of α-globin-3′HVR Probe for DNA Fingerprinting in Forensic Sci ence

Li Boling, Ni Jintang, Ye Jian, Ding Yan, Chu Xiaolan   

  1. Institute of Forensic Science,Ministry of Public Security,Beijing 100038
  • Received:1900-01-01 Revised:1900-01-01

Abstract: Using α-globin-3′HVR as the molecular hybridization probe,A clear and readable DNA fingerprint has been obtained.Based on the DNA fingerprint analysis of 200 unrelated individuals living in Beijing area,the probability of chance associati on of two random individuals was 4.0×10 -12. The study of 32 related individuals of 6 families showed that the inheritanc e of DNA fingerprint bands conformed to the Mendelian law.The method is reliable for the individual identification and paternity test.It provides a scientific b asis for solving cases such as rape,homicide etc.and it has been used in our act ual case work.

Key words: Paternity test, α-globin-3′HVR probe, DNA fingerprint, Probability of chance association.Individ ual identificafion