生命与健康大数据中心资源

doi:10.16288/j.yczz.18-190

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Hereditas(Beijing) ›› 2018, Vol. 40 ›› Issue (11): 1039-1043.doi: 10.16288/j.yczz.18-190

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The BIG Data Center’s database resources

Yuansheng Zhang^1,^2,³,Lin Xia^1,^2,³,Jian Sang^1,^2,³,Man Li^1,^2,³,Lin Liu^1,^2,³,Mengwei Li^1,^2,³,Guangyi Niu^1,^2,³,Jiabao Cao^1,^2,³,Xufei Teng^1,^2,³,Qing Zhou^1,^2,³,Zhang Zhang^1,^2,³()

^1. BIG Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
^2. CAS Key Laboratory of Genomics and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
^3. University of Chinese Academy of Sciences, Beijing 100049, China

Received:2018-07-05 Revised:2018-09-12 Online:2018-11-20 Published:2018-09-18
Contact: Zhang Zhang E-mail:zhangzhang@big.ac.cn
Supported by:
Supported by Strategic Priority Research Program of the Chinese Academy of Sciences(XDA19050302);Supported by Strategic Priority Research Program of the Chinese Academy of Sciences(XDB13040500);Supported by Strategic Priority Research Program of the Chinese Academy of Sciences(XDA08020102);the National Key Research & Development Program of China(2016YFC0901603);the 13th Five-year Informatization Plan of Chinese Academy of Sciences(XXH13505-05)

Abstract

Abstract:

Omics data in life and health sciences are of fundamental significance for scientific research and biomedical technology development. However, there is yet to be a platform for biological data management and sharing in China, making it difficult to meet the development needs of biomedical and related fields and consequently leading to severe issues in big data management, sharing and translation. To address these issues, Beijing Institute of Genomics (BIG) of Chinese Academy of Sciences founded the BIG Data Center (BIGD) in 2016, which is dedicated to establish a biological big data management platform and multi-omics databases, with a particular focus on national population healthcare and important strategic biological resources. In this paper, we describe core database resources in BIGD, including GSA (Genome Sequence Archive), GWH (Genome Warehouse), GVM (Genome Variation Map), GEN (Gene Expression Nebulas), MethBank (Methylation Bank), BioCode and Science Wikis. Taken together, all these resources provide a series of services for data deposition, integration and sharing, laying solid foundations for enhancing national biological science data management and further promoting the construction of national bioinformatics center.

Key words: big data, omics, data sharing, data resource, bioinformatics

Yuansheng Zhang,Lin Xia,Jian Sang,Man Li,Lin Liu,Mengwei Li,Guangyi Niu,Jiabao Cao,Xufei Teng,Qing Zhou,Zhang Zhang. The BIG Data Center’s database resources[J]. Hereditas(Beijing), 2018, 40(11): 1039-1043.

References

[1]	BIG Data Center Members . The BIG Data Center: from deposition to integration to translation. Nucleic Acids Res, 2017,45(Database Issue):D18-D24.
[2]	BIG Data Center Members . Database resources of the BIG Data Center in 2018. Nucleic Acids Res, 2018,46(Database Issue):D14-D20.
[3]	Wang Y, Song F, Zhu J, Zhang S, Yang Y, Chen T, Tang B, Dong L, Ding N, Zhang Q, Bai Z, Dong X, Chen H, Sun M, Zhai S, Sun Y, Yu L, Lan L, Xiao J, Fang X, Lei H, Zhang Z, Zhao W . GSA: Genome sequence archive. Genom Proteom Bioinf, 2017,15(1):14-18.
[4]	Zhang S, Chen T. Zhu J, Zhou Q, Chen X, Wang Y, Zhao W . GSA: Genome Sequence Archive. Hereditas (Beijing), 2018,40(11):1044-1047.
[4]	张思思, 陈婷婷, 朱军伟, 周晴, 陈旭, 王彦青, 赵文明 . GSA: 组学原始数据归档库. 遗传, 2018,40(11):1044-1047.
[5]	Song S, Tian D, Li C, Tang B, Dong L, Xiao J, Bao Y, Zhao W, He H, Zhang Z . Genome Variation Map: a data repository of genome variations in BIG Data Center. Nucleic Acids Res, 2018,46(Database Issue):D944-D949.
[6]	Song S, Teng X, Xiao J . Database resources of the reference genome and genetic varia-tion maps for the Chinese population. Hereditas (Beijing), 2018,40(11):1048-1054.
[6]	宋述慧, 滕徐菲, 肖景发 . 中国人群参考基因组及基因组变异图谱资源库. 遗传, 2018,40(11):1048-1054.
[7]	Ling Y, Jin Z, Su M, Zhong J, Zhao Y, Yu J, Wu J, Xiao J . VCGDB: a dynamic genome database of the Chinese population. BMC Genomics, 2014,15:265.
[8]	Bai B, Zhao W, Tang B, Wang Y, Wang L, Zhang Z, Yang H, Liu Y, Zhu J, Irwin D, Wang G, Zhang Y . DoGSD: the dog and wolf genome SNP database. Nucleic Acids Res, 2015,43(Database Issue):D777-D783.
[9]	Luo H, Zhao W, Wang Y, Xia Y, Wu X, Zhang L, Tang B, Zhu J, Fang L, Du Z, Bekele W, Tai S, Jordan D, Godwin I, Snowdon R, Mace E, Jing H, Luo J . SorGSD: a sorghum genome SNP database. Biotechnol Biofuel, 2016,9(1):6.
[10]	Sheng X, Wu J, Sun Q, Xian F, Li X, Sun M, Fang W, Chen M, Yu J, Xiao J . MTD: a mammalian transcriptomic database to explore gene expression regulation. Brief Bioinform, 2017,18(1):28-36.
[11]	Xia L, Zou D, Sang J, Xu X, Yin H, Li M, Wu S, Hu S, Hao L , Zhang Z.Rice Expression Database (RED): an integrated RNA-Seq-derived gene expression database for rice. J Genet Genomics, 2017,44(5):235-241.
[12]	Sang J, Wang Z, Li M, Cao J, Niu G, Xia L, Zou D, Wang F, Xu X, Han X, Fan J, Yang Y, Zuo W, Zhang Y, Zhao W, Bao Y, Xiao J, Hu S, Hao L, Zhang Z . ICG: a wiki-driven knowledgebase of internal control genes for RT-qPCR normalization. Nucleic Acids Res, 2017,46(Database Issue):D121-D126.
[13]	Zou D, Sun S, Li R, Liu J, Zhang J, Zhang Z . MethB

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