遗传 ›› 2013, Vol. 35 ›› Issue (3): 307-314.doi: 10.3724/SP.J.1005.2013.00307

• 综述 • 上一篇    下一篇

植物非特异脂质转运蛋白研究现状与展望

刘芳,卢长明   

  1. 中国农业科学院油料作物研究所, 农业部油料作物生物学与遗传育种重点实验室, 武汉 430062
  • 收稿日期:2012-06-04 修回日期:2012-07-25 出版日期:2013-03-20 发布日期:2013-03-25
  • 通讯作者: 卢长明 E-mail:cmlu@oilcrops.cn
  • 基金资助:

    油菜KCS基因家族底物特异性及异位表达研究项目(编号:31100190) 资助

An overview of non-specific lipid transfer protein in plant

LIU Fang, LU Chang-Ming   

  1. Oil Crop Research Institute of the Chinese Academy of Agricultural Science, Key Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture, Wuhan 430062, China
  • Received:2012-06-04 Revised:2012-07-25 Online:2013-03-20 Published:2013-03-25

摘要: 植物非特异脂质转运蛋白(nsLTP)是一类含量丰富的小分子碱性蛋白, 能够在体外与多种疏水分子可逆地结合。目前已从多种植物中分离到9种类型的nsLTP基因。所有nsLTP蛋白质都具有8个半胱氨酸残基模体的保守结构, 它们的三维结构内部有一个具有脂质结合位点的疏水腔。根据基因结构、表达、调控和体外活性等研究, nsLTP被认为可能与蜡质合成与运输、抗逆、抗病以及生殖发育等重要生理过程有关。文章全面介绍nsLTP基因及其蛋白质研究的最新进展, 内容包括基本特征、分类、基因表达、基因克隆与功能研究等, 最后对今后的研究方向进行了讨论和展望。

关键词: 非特异脂质转运蛋白, 家族, 表达, 功能

Abstract: Plant non-specific lipid transfer proteins (nsLTPs) are a group of abundantly expressed small basic proteins, which can reversibly bind and transport hydrophobic molecules in vitro. Nine types of nsLTP have been identified from a variety of plants. All the type of nsLTPs possesses the conserved eight cysteine residue motif with a three-dimensional structure of an internal hydrophobic cavity and the lipid binding site. Based on the growing knowledge about the structure, gene expression, regulation and in vitro activity, nsLTPs are considered to play a role in key processes of plant physiology, including wax synthesis and transport, abiotic stress resistance, disease resistance, and plant reproduction. This review aims at presenting comprehensive information of key topics, including basic features, classification, gene cloning, expression profiles, and functional studies of nsLTP. Finally the perspectives were included on the future study of nsLTP family.

Key words: nsLTP, family, expression, function

中图分类号: