遗传 ›› 2014, Vol. 36 ›› Issue (10): 974-984.doi: 10.3724/SP.J.1005.2014.0974
冉茂良1,2,陈斌1,2,尹杰3,4,杨岸奇1,2,李智1,2,蒋明1,2
收稿日期:2014-05-04
出版日期:2014-10-20
发布日期:2014-10-20
通讯作者:
陈斌,教授,博士生导师,研究方向：猪的遗传育种。E-mail: chenbin7586@126.com
E-mail:ranmaoliang0903@126.com
作者简介:冉茂良,博士研究生,专业方向：猪的遗传育种。E-mail: ranmaoliang0903@126.com
基金资助:Maoliang Ran1, 2, Bin Chen1, 2, Jie Yin3, 4, Anqi Yang1, 2, Zhi Li1, 2, Ming Jiang1, 2
Received:2014-05-04
Online:2014-10-20
Published:2014-10-20
摘要： MicroRNA(miRNA)是一类长约22 nt的非编码小RNA,广泛存在于各种生物中,调节生物体生长、发育和凋亡等过程。研究表明,miRNA在猪肌肉、脂肪、生殖系统以及免疫系统等的发育过程中发挥着重要的调控作用。此外,高通量的新一代测序技术在猪miRNA的挖掘和差异表达研究中发挥着巨大的作用。文章综述了高通量的新一代测序技术在挖掘猪miRNA中的应用以及一些miRNA在猪脂肪代谢、肌肉发育、卵母细胞成熟和B、T淋巴细胞发育中的调控作用,旨在为猪miRNA的研究提供参考,为利用miRNA调控和改善猪肉品质、生长性能、繁殖性能以及免疫机能提供理论基础和研究思路。
冉茂良,陈斌,尹杰,杨岸奇,李智,蒋明. 猪microRNA组学研究进展[J]. 遗传, 2014, 36(10): 974-984.
Maoliang Ran, Bin Chen, Jie Yin, Anqi Yang, Zhi Li, Ming Jiang. Advances in porcine miRNAome[J]. HEREDITAS(Beijing), 2014, 36(10): 974-984.
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