摘要： 为了探讨肺腺癌细胞系中金属蛋白酶的活性与其转移能力之间的相关性，选取9个转移能力不同的肺腺癌细胞系，分别对它们所分泌的金属蛋白酶MMP－2、MMP－9进行活性分析。结果发现，金属蛋白酶的活性与肺腺癌细胞系的转移能力有一定的相关性，其中MMP－9的活性与肺腺癌细胞系的转移相关性更显著。
Abstract:To investigate the relationship between the MMP activities and metastatic ability in human lung adenocarcinoma cell lines with differential metastatic potential.Nine lung adenocarcinoma cell lines were tested for their MMP activities by zymographic analysis methods.The MMP production capabilities of carcinoma cells rose following the increase of their metastatic potentials.The result suggested that there was some relationship between MMP－9 activties and metastatic potential in human lung adenocarcinomas.