摘要： 雌激素受体（estrogen receptor，ESR）能调控雌激素的合成，影响繁殖功能。将ESR基因作为控制猪产仔数的候选基因，分析其Pvu II多态性与高产猪种莱芜猪和国外引进猪种长白猪产仔数的关系。序列分析发现，PCR扩增区56bp的Pvu II酶切片段位于RFLP分析获得的37kb正向序列的起始部分。因ESR基因在高产仔数的莱芜猪中的Pvu II多态性分布不能证实B基因为优势基因，故推测37kb条带对该猪种产仔数可能不起决定作用。
Abstract:Estrogen receptor (ESR) can regulate the synthesis of oestrogen and affect the reproduction of swine.The relationship between PvuII polymorphisms at estrogen receptor gene and litter size was analyzed in Laiwu breed and Landrace breed by candidate gene method.The results were shown that 56bp of PvuII polymorphisms was the same as the beginning sequence of 37kb of RFLP.The distribution of PvuII polymorphisms also could not prove that B gene was a superior gene,and there was no decisive effect of 37kb band on litter size in pigs.