遗传 ›› 2005, Vol. 27 ›› Issue (3): 481-486.

• 专论与综述 • 上一篇    下一篇

生长分化因子9基因的分子生物学

吴泽辉1;储明星2;李学伟1   

  1. 1.四川农业大学动物科技学院, 雅安 625014; 2. 中国农业科学院畜牧研究所,北京 100094
  • 收稿日期:2004-04-21 修回日期:2005-01-04 出版日期:2005-06-10 发布日期:2005-06-10
  • 通讯作者: 储明星

Molecular Biology of Growth Differentiation Factor 9 Gene

WU Ze-Hui1; CHU Ming-Xing2; LI Xue-Wei1   

  1. 1. College of Animal Science and Technology, Sichuan Agricultural University, Ya’an 625014, China;
  • Received:2004-04-21 Revised:2005-01-04 Online:2005-06-10 Published:2005-06-10
  • Contact: CHU Ming-Xing

摘要: 生长分化因子9是卵母细胞分泌的一种生长因子,它对卵泡的生长分化起着重要作用。本文介绍了生长分化因子9的结构、功能和调控,生长分化因子9基因的克隆及基因结构、发育性表达和作用、定位和多态性,并讨论了该基因与哺乳动物繁殖性能的关系。

关键词: 生长分化因子9, 生长分化因子9基因, 繁殖性能

Abstract: Growth differentiation factor 9 (GDF9) secreted by oocyte is essential for follicular growth and differentiation. This review introduced the structure, function and regulation of GDF9, as well as the cloning and structure, developmental expression, mapping and polymorphism of GDF9 gene. The relationship between GDF9 gene and reproductive performance was also discussed in mammals.

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