重复序列及异染色质化在植物性染色体重组抑制中的作用

遗传 ›› 2010, Vol. 32 ›› Issue (1): 25-30.

重复序列及异染色质化在植物性染色体重组抑制中的作用

高武军¹,谢璐²,邓传良³,卢龙斗³

1. 河南师范大学
2.
3. 河南师范大学生命科学学院

收稿日期:2009-05-27 修回日期:2009-08-17 出版日期:2010-01-20 发布日期:2010-01-20
通讯作者: 卢龙斗 E-mail:lld5910@yahoo.com

Role of repetitive sequence and heterochromatize in recombination suppression of plant sex chromosomes

Received:2009-05-27 Revised:2009-08-17 Online:2010-01-20 Published:2010-01-20

摘要/Abstract

摘要：

重组抑制是植物性染色体由常染色体进化而来的前提条件，性别决定位点区域发生的重组抑制使早期的性染色体发生了退化和分化。研究表明，重组抑制的产生和染色体上一系列行为的发生有着密切的关系，如重复序列的累积、异染色质化及DNA的甲基化。转座因子和卫星DNA等重复序列的累积使早期植物性染色体形态和分子结构发生了分化，同时还导致性染色体的异染色质化，抑制了性染色体间的重组的发生。本文较全面综述了这一领域的进展，并对DNA甲基化在植物性染色体重组抑制形成过程中可能的作用进行了简要分析。

关键词: 性染色体；重组抑制；重复序列；异染色质；甲基化

Abstract:

Suppression of recombination is the prerequisite for plant sex chromosome evolution from a pair of autosomes. Recombination suppression around the locus controlling sex determination lead to sex chromosome degeneration and differentiation. Important events such as repetitive sequence accumulation, heterochromatize and DNA methylation have relation to recombination suppression . Accumulation of repetitive DNA sequence, including transposable elements and satellite DNA, lead to primitive sex chromosome differentiated on morphological and molecular structure, and also gave rise to chromosome heterochromatize, thereafter recombination between sex chromosomes was suppressed. Here, we review the advances in this field, meanwhile, function of DNA methylation in recombination suppression is being analysed briefly.

Key words: sex chromosome, recombination suppression, repetitive sequence, heterochromatin, methylation

高武军，谢璐，邓传良，卢龙斗. 重复序列及异染色质化在植物性染色体重组抑制中的作用[J]. 遗传, 2010, 32(1): 25-30.