[1] Powell AP, Nelson RS, De B, Hoffmann N, Rogers SG, Fraley RT, Beachy RN. Delay of disease development in transgenic plants that express the tobacco mosaic virus coat protein gene. Science, 1986, 232(4751): 738-743.[2] 周北雁, 李毅, 陈章良. 北京大学的抗病毒转基因作物. 生物技术通报, 1999, (3): 42-45.[3] Kaniewski W, Ilardi V, Tomassoli L, Mitsky T, Layton J, Barba M. Extreme resistance to cucumber mosaic virus (CMV) in transgenic tomato expressing one or two viral coat proteins. Mol Breed, 1999, 5(2): 111-119.[4] Zrachya A, Kumar PP, Ramakrishnan U, Levy Y, Loyter A, Arazi T, Lapidot M, Gafni Y. Production of siRNA targeted against TYLCV coat protein transcripts leads to silencing of its expression and resistance to the virus. Transgenic Res, 2007, 16(3): 385-398.[5] Tamarzizt HB, Chouchane SG, Lengliz R, Maxwell DP, Marrakchi M, Fakhfakh H, Gorsane F. Use of tomato leaf curl virus (TYLCV) truncated Rep gene sequence to engineer TYLCV resistance in tomato plants. Acta Virol, 2009, 53(2): 99-104.[6] 朱秋菊. 转核酶基因、反义和正义CMV-CP基因番茄的抗黄瓜花叶病毒(CMV)研究[学位论文]. 北京: 中国科学院研究生院(植物研究所), 2005.[7] Itaya A, Bundschuh R, Archual AJ, Joung JG, Fei ZJ, Dai XB, Zhao PX, Tang YH, Nelson RS, Ding B. Small RNAs in tomato fruit and leaf development. Biochim Biophys Acta, 2008, 1779(2): 99-107.[8] Yin ZJ, Li CH, Han XL, Shen FF. Identification of con-served microRNAs and their target genes in tomato (Lycopersicon esculentum). Gene, 2008, 414(1-2): 60-66.[9] Bazzini AA, Asís R, González V, Bassi S, Conte M, Soria M, Fernie AR, Asurmendi S, Carrari F. miSolRNA: A tomato micro RNA relational database. BMC Plant Biol, 2010, 10(1): 1-7.[10] Zhang XH, Li HX, Zhang JH, Zhang CJ, Gong PJ, Ziaf K, Xiao FM, Ye ZB. Expression of artificial microRNAs in tomato confers efficient and stable virus resistance in a cell-autonomous manner. Transgenic Res, 2011, 20(3): 569-581.[11] Jongedijk E, Tigelaar H, Vanroekel JSC, Bresvloemans SA, Dekker I. Synergistic activity of chitinases and β-1,3- glucanases enhances fungal resistance in transgenic tomato plants. Euphytica, 1995, 85(1-3): 173-180.[12] Chen SC, Liu AR, Wang F H, Ahammed G J. Combined overexpression of chitinase and defensin genesin transgenic tomato enhances resistance to Botrytis cinerea. Afr J Biotechnol, 2009, 8(20): 5182-5188.[13] Thomzik JE, Stenzel K, Stöcker R, Schreier PH, Hain R, Stahl DJ. Synthesis of a grapevine phytoalexin in transgenic tomatoes (Lycopersicon esculentum Mill.) conditions resistance against Phytophthora infestans. Physiol Mol Plant Pathol, 1997, 51(4): 265-278.[14] Khan RS, Nakamura I, Mii M. Development of disease-resistant marker-free tomato by R/RS site-specific recombination. Plant Cell Rep, 2011, 30(6): 1041-1053.[15] Tai TH, Dahlbeck D, Clark ET, Gajiwala P, Pasion R, Whalen MC, Stall RE, Staskawicz BJ. Expression of the Bs2 pepper gene confers resistance to bacterial spot disease in tomato. Proc Natl Acad Sci USA, 1999, 96(24): 14153-14158.[16] Jan PS, Huang HY, Chen HM. Expression of a synthesized gene encoding cationic peptide cecropin B in transgenic tomato plants protects against bacterial diseases. Appl Environ Microbiol, 2010, 76(3): 769-775.[17] Balaji V, Mayrose M, Sherf O, Jacob-Hirsch J, Eichenlaub R, Iraki N, Manulis-Sasson S, Rechavi G, Barash I, Sessa G. Tomato transcriptional changes in response to Clavibacter michiganensis subsp. michiganensis reveal a role for ethylene in disease development. Plant Physiol, 2008, 146(4): 1797-1809.[18] Rezk AAS, Abdallah NA, Abdel AM, Nakhla MK, Mazyad HM, Maxwell DP. Transgene-mediated RNA silencing of TYLCV genes affecting the accumulation of viral DNA in plants. Arab J Biotech, 2006, 9(1): 143-158.[19] Koshino-Kimura Y, Takenaka K, Domoto F, Ohashi M, |