注意缺损多动障碍关联于DXS7位点

遗传 ›› 1999, Vol. 21 ›› Issue (2): 16-615.

注意缺损多动障碍关联于DXS7位点

杨辉; 嵇庆; 张锡然; 单祥年 YANG Hui;JI Qing;ZHANG Xi-ran

1.上海市精神卫生中心，上海200030 2.上海医科大学精神医学教研室，上海200032 3.复旦大学遗传研究所，上海200433　　　　　 1.Shanghai Mental Health Center,Shanghai200030 2.Department of Mental Health,Shanghai Medical University,Shanghai200032 3.Genetics Institute,Fudan University,Shanghai200433

收稿日期:1900-01-01 出版日期:1999-04-10 发布日期:1999-04-10

Association of Attention-Deficit Hyperactivity Disorder and the DXS7 Locus

Received:1900-01-01 Online:1999-04-10 Published:1999-04-10

摘要/Abstract

摘要： 用单细胞凝胶电泳法检测了稀土化合物氯化钇和氯化镨对人外周血淋巴细胞的DNA损伤效应。结果表明,与对照相比,3种不同浓度的氯化钇和氯化镨均可引起淋巴细胞DNA受损后DNA迁移率的显著升高,受损伤细胞的百分率与对照差异明显,提示氯化钇和氯化镨具有一定的遗传毒性。
Abstract:The effect of DNA damage in human lymphocytes induced by yttrium chloride and praseodymium chloride was detected using SCG assay.The results showed that a highly significant increase in DNA migration in DNA-damaged lymphocytes was induced by three different concentrations of yttrium and praseodymium compared with the control,The percentage of DNA-damaged have genetic toxicity.The relevant points to this study are discussed.

关键词: 氯化镨
Key words, Single cell gel electrophoresis, 氯化钇, DNA迁移率, 单细胞凝胶电泳, 抗体库技术, 单链抗体, pFUW80

Key words: Single-chain antibody, Antibody library, pFUW80

杨辉，嵇庆，张锡然，单祥年. 注意缺损多动障碍关联于DXS7位点[J]. 遗传, 1999, 21(2): 16-615.

YANG Hui, JI Qing, ZHANG Xi-ran. Association of Attention-Deficit Hyperactivity Disorder and the DXS7 Locus [J]. HEREDITAS, 1999, 21(2): 16-615.