遗传 ›› 2000, Vol. 22 ›› Issue (1): 11-14.

• 论文 • 上一篇    下一篇

广州汉族人群DYS19、DYS389Ⅰ/Ⅱ、DYS390多态性及其单体型

唐双柏1;郭景元1;刘超2;梁赏猷2;王穗保2 TANG Shuang-bo1;GUO Jing-yuan1;LIU Chao1;LIANG Shang-you2;WANG Sui-bao2   

  1. 1.中山医科大学法医系,广东广州 510089 2.广州市公安局刑事科学技术研究所,广东 广州 510030 1.Faculty of Forensic Medicine,Sun Yat?sen University of Medical Sciences,Guangzhou 510089 2.Institute of Criminal Sciences,Guangzhou 510030, China
  • 收稿日期:1900-01-01 出版日期:2000-02-10 发布日期:2000-02-10

Y-DNA STRs Polymorphisms and Haplotypes in Guangzhou Han Population

  • Received:1900-01-01 Online:2000-02-10 Published:2000-02-10

摘要: 用PCR结合PAGE技术观察111例广州汉族男性DYS19、DYS389Ⅰ/Ⅱ、DYS390等位基因及单体型分布状况。结果显示:广州地区汉族男性DYS19基因座观察到5种等位基因,DYS389Ⅰ观察到4种等位基因,DYS389Ⅱ观察到5种等位基因,DYS390观察到5种等位基因;χ2检验表明上述各等位基因频率分布与其他地区人群存在明显的差异。此外,还观察到72种由上述基因座共同构成的单体型,单体型多样性达0.953。
Abstract: In order to apply a set of useful and high polymorphic Y?STRs in forensic practice and genetic analysis,we performed a population genetic study from Chinese.The allele distributions of the systems DYS19、DYS389Ⅰ/Ⅱ、and DYS390 were investigated in sample of 111 unrelated males from the area of Guangzhou, China.PCR products were detected using polyacrylamide gel electrophoresis and silver staining.5、4、5、5 alleles were observed in locus DYS19、DYS389Ⅰ、DYS389Ⅱ、DYS390 respectively.Different allele frequency distributions were observed when compared to other population.Haplotype frequency date of 72 different types were obtained.

关键词: Y染色体, 短串联重复序列, 遗传多态性, 广州汉族人
Key words,
单体型