摘要： 妊高征具有明显的遗传倾向，其发病机理尚不清楚。本文综述了妊高征易感基因的研究进展，讨论了与高血压、内皮细胞损害、免疫反应失调相关基因和妊高征的关联，并论述了这些基因突变或多态性对妊高征的影响。
Abstract:The etiology and pathogenesis of pregnancy induced hypertension (PIH) remain still unknown.In recent years an increasing amount of evidence supports the concept that PIH is a complex genetic susceptibility disease.The progress in susceptibility gene for PIH is reviewed.The associations between the genes for hypertension,endothelial?cell dysfunction.,immune maladaptation?interaction and PIH have been recently investigated.Meanwhile,the paper evaluates the influences of mutations and polymorphism at the genes on PIH.