遗传 ›› 2004, Vol. 26 ›› Issue (3): 409-413.

• 论文 • 上一篇    下一篇

tmRNA的结构与功能

田 云;卢向阳;易 克;唐勇军;陈惠明TIAN Yun;LU Xiang-Yang;YI Ke;TANG Yong-Jun;CHEN Hui-Ming   

  1. 湖南农业大学生命科学楼生化与发酵工程实验室,长沙 410128 Biochemistry & Fermentation Lab of Life Science, Hunan Agricultural University , Changsha 410128,China
  • 收稿日期:1900-01-01 出版日期:2004-06-10 发布日期:2004-06-10

The Structure and Function of tmRNA

  • Received:1900-01-01 Online:2004-06-10 Published:2004-06-10

摘要: tmRNA是一类具有类似tRNA分子和mRNA分子双重功能的小分子RNA,它在一种特殊的翻译模式——反式翻译模式过程中发挥重要作用。最近又发现它与基因的表达调控及细胞周期的调控等生命过程密切相关。因此,关于tmRNA的研究已经引起了研究者的高度重视,它将是RNA组学研究的一个重要内容。文章主要论述了近年来关于tmRNA结构和功能方面的一些研究进展。Abstract: tmRNA is a dual small RNA similar to a tRNA and a mRNA which plays an important role in an unusual mode of translation——trans translation. Recently, it was found that tmRNA had something to do with regulating gene expression and cell cycle. So the researchers have paid much attention on such area. Furthermore, it is an important part in RNomics era. This article reviews the progress about the structure and function of tmRNA in recent years.



关键词: 核蛋白S1
Key words,
延伸因子-Tu, SmpB蛋白, 反式翻译, tmRNA